HitPredict

Interactor 1: ROR1 (Q01973)
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)
Gene: ROR1

Interactor 2: DUS19 (Q8WTR2)
Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1)
Gene: DUSP19

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 937 Hs			1 217
+	Hs
		326693 ROR1_HUMAN (30-937): 0: 770: 100.00		DUS14_HUMAN (62-216): 2.73e-65: 202: 30.32
+	Hs
		1034179 ROR1_HUMAN (30-937): 0: 770: 100.00		DUS18_HUMAN (49-216): 1.32e-60: 189: 27.98
+	Hs
		1034193 ROR1_HUMAN (30-937): 0: 770: 100.00		DUS21_HUMAN (58-216): 8.91e-59: 185: 29.56
+	Hs
		1034182 ROR1_HUMAN (30-937): 0: 770: 100.00		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		1034168 ROR1_HUMAN (30-937): 0: 770: 100.00		DUS29_HUMAN (64-204): 1.58e-53: 172: 30.20
+	Hs
		1034300 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS19_HUMAN (1-217): 9.39e-89: 262: 100.00
+	Hs
		703929 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS1_HUMAN (18-217): 1.24e-74: 231: 29.85
+	Hs
		326694 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS14_HUMAN (62-216): 2.73e-65: 202: 30.32
+	Hs
		1034248 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS6_HUMAN (47-214): 8.81e-60: 193: 33.33
+	Hs
		1034295 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS18_HUMAN (49-216): 1.32e-60: 189: 27.98
+	Hs
		1034344 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS21_HUMAN (58-216): 8.91e-59: 185: 29.56
+	Hs
		1034302 ROR2_HUMAN (1-936): 0: 664: 55.33		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		1034264 ROR2_HUMAN (1-936): 0: 664: 55.33		DUS29_HUMAN (64-204): 1.58e-53: 172: 30.20
+	Hs
		1147384 EPHA7_HUMAN (12-807): 5.01e-173: 531: 19.44		DUS18_HUMAN (49-216): 1.32e-60: 189: 27.98
+	Hs
		1147391 EPHA7_HUMAN (12-807): 5.01e-173: 531: 19.44		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		710641 EPHA3_HUMAN (12-808): 1e-169: 522: 19.56		DUS18_HUMAN (49-216): 1.32e-60: 189: 27.98
+	Hs
		1147419 EPHA7_HUMAN (12-807): 5.01e-173: 531: 19.44		DUS26_HUMAN (63-205): 2e-55: 177: 30.20
+	Hs
		710661 EPHA3_HUMAN (12-808): 1e-169: 522: 19.56		DUS21_HUMAN (58-216): 8.91e-59: 185: 29.56
+	Hs
		710646 EPHA3_HUMAN (12-808): 1e-169: 522: 19.56		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		179623 MUSK_HUMAN (30-758): 1.91e-167: 512: 27.31		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83