HitPredict

Interactor 1: ANK3 (G5E8K5)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Interactor 2: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Pkinase, Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1961 Mm			1 1323
+	Hs
		1356406 ANR50_HUMAN (1-419): 1.02e-109: 386: 29.21		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Hs
		310105 TNKS1_HUMAN (1-345): 1.49e-76: 282: 29.23		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Hs
		257718 ANR17_HUMAN (2-349): 1.25e-62: 240: 27.10		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Mm
		949370 ANK2_MOUSE (871-1960): 4.17e-13: 77.7: 9.61		TNIK_MOUSE (1-1323): 0: 1277: 100.00
+	Hs
		1021472 ANK3_HUMAN (791-1955): 1.51e-10: 69.2: 10.06		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Hs
		965172 ANK2_HUMAN (844-1949): 1.12e-09: 66.1: 9.22		TNIK_HUMAN (1-1323): 0: 1245: 95.15
+	Hs
		324897 ANFY1_HUMAN (2-239): 1.4e-24: 114: 17.89		M4K4_HUMAN (1-1323): 0: 1016: 62.17
+	Hs
		1023132 ANFY1_HUMAN (2-239): 1.4e-24: 114: 17.89		STK4_HUMAN (5-470): 3.93e-119: 382: 32.59
+	Hs
		1027449 ANFY1_HUMAN (2-239): 1.4e-24: 114: 17.89		STK3_HUMAN (4-496): 1.39e-117: 377: 30.12