HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30562941, 28634551
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0016358 - dendrite development GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1340 Mm			1 817
+	Hs
		1368714 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		DLG3_HUMAN (267-734): 3.47e-40: 161: 14.72
+	Mm
		104585 SYGP1_MOUSE (1-1340): 0: 1071: 100.00		DLG1_MOUSE (80-763): 3.42e-35: 146: 10.27
+	Mm
		104504 SYGP1_MOUSE (1-1340): 0: 1071: 100.00		DLG3_MOUSE (172-707): 5.05e-35: 145: 12.56
+	Mm
		104620 SYGP1_MOUSE (1-1340): 0: 1071: 100.00		DLG2_MOUSE (85-696): 9.3e-33: 138: 12.36
+	Mm
		104543 SYGP1_MOUSE (1-1340): 0: 1071: 100.00		DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04
+	Hs
		1348443 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		LNX1_HUMAN (236-773): 1.12e-33: 140: 11.17
+	Hs
		1006093 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		DLG4_HUMAN (438-714): 1.47e-29: 127: 16.03
+	Rn
		1224329 SYGP1_RAT (1-1298): 0: 1028: 98.69		DLG3_RAT (172-707): 3.43e-35: 145: 12.56
+	Hs
		1325754 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		LNX2_HUMAN (195-645): 8.41e-25: 112: 10.17
+	Rn
		723903 SYGP1_RAT (1-1298): 0: 1028: 98.69		DLG4_RAT (381-806): 6.58e-31: 132: 11.04
+	Mm
		1190099 DAB2P_MOUSE (97-1339): 0: 849: 47.75		DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04
+	Hs
		936478 NGAP_HUMAN (84-1338): 0: 796: 43.40		AFAD_HUMAN (397-798): 1.75e-38: 157: 18.69
+	Hs
		1401133 NGAP_HUMAN (84-1338): 0: 796: 43.40		MAGI1_HUMAN (453-794): 2.69e-17: 89.3: 12.64
+	Hs
		862951 IQGA1_HUMAN (232-723): 2.63e-106: 373: 14.29		NEB2_HUMAN (1-817): 4.8e-111: 359: 95.84
+	Mm
		1190773 IQGA2_MOUSE (216-731): 1.42e-115: 399: 14.09		DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04
+	Mm
		1223783 RASL1_MOUSE (162-702): 6.13e-120: 395: 18.95		DLG4_MOUSE (381-806): 6.82e-31: 132: 11.04
+	Hs
		862915 IQGA1_HUMAN (232-723): 2.63e-106: 373: 14.29		LNX1_HUMAN (236-773): 1.12e-33: 140: 11.17
+	Dm
		119051 Q9VBJ2_DROME (364-749): 2.9e-84: 307: 21.43		M9NFI9_DROME (265-816): 1.06e-53: 204: 34.47
+	Hs
		862948 IQGA1_HUMAN (232-723): 2.63e-106: 373: 14.29		MAGI1_HUMAN (453-794): 2.69e-17: 89.3: 12.64
+	Hs
		637890 NF1_HUMAN (408-712): 2.97e-82: 301: 23.21		PTN13_HUMAN (65-778): 2.01e-20: 99.7: 8.63