HitPredict

Interactor 1: CDK13 (Q14004)
Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)
Gene: CDK13

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1512 Hs			1 972
+	Hs
		531149 CDK13_HUMAN (1-1512): 0: 912: 100.00		EF2_HUMAN (111-957): 0: 915: 38.16
+	Hs
		625443 CDK2_HUMAN (702-1004): 6.13e-140: 433: 41.45		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		658947 MK01_HUMAN (704-1041): 4.63e-136: 425: 32.85		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		414924 CDK1_HUMAN (702-1003): 1.17e-132: 414: 39.80		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		841734 CDK9_HUMAN (702-1030): 1.93e-122: 389: 44.78		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		531033 CDK2_HUMAN (702-1004): 6.13e-140: 433: 41.45		EF2_HUMAN (111-957): 0: 915: 38.16
+	Rn
		398607 MK03_RAT (696-1046): 4.78e-134: 421: 31.07		EF2_RAT (111-957): 0: 916: 38.16
+	Zm
		80592 C0P901_MAIZE (635-1094): 7.6e-122: 394: 34.34		B6U0S1_MAIZE (111-957): 0: 896: 36.78