HitPredict

Interactor 1: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Interactor 2: KLK15 (Q9H2R5)
Kallikrein-15 (EC 3.4.21.-) (ACO protease)
Gene: KLK15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1400 Hs			1 256
+	Hs
		457950 EPHA3_HUMAN (614-1375): 1.13e-170: 537: 17.07		TRY1_HUMAN (1-256): 2.11e-119: 342: 42.25
+	Hs
		457948 EPHA1_HUMAN (727-1375): 1.37e-133: 438: 23.79		TRY1_HUMAN (1-256): 2.11e-119: 342: 42.25
+	Hs
		449591 FGFR3_HUMAN (1015-1400): 1.19e-113: 379: 32.20		KLK1_HUMAN (1-256): 5.38e-105: 306: 37.64
+	Hs
		455633 FGFR3_HUMAN (1015-1400): 1.19e-113: 379: 32.20		KLK3_HUMAN (1-256): 1.76e-102: 300: 40.00
+	Hs
		1432127 PLXA1_HUMAN (382-925): 5.05e-43: 174: 21.82		KLK15_HUMAN (1-256): 1.44e-112: 325: 100.00
+	Hs
		465698 IGF1R_HUMAN (1072-1343): 3.58e-52: 204: 37.93		KLK5_HUMAN (5-256): 9.44e-97: 286: 40.55
+	Hs
		449629 PLXA1_HUMAN (382-925): 5.05e-43: 174: 21.82		KLK1_HUMAN (1-256): 5.38e-105: 306: 37.64
+	Hs
		455639 PLXA3_HUMAN (375-923): 1.44e-37: 156: 21.06		KLK3_HUMAN (1-256): 1.76e-102: 300: 40.00
+	Hs
		175341 PLXB2_HUMAN (508-997): 1.63e-24: 114: 20.94		TMPS3_HUMAN (4-256): 2.48e-99: 298: 30.45
+	Hs
		1055115 TYRO3_HUMAN (1062-1348): 1.01e-59: 224: 41.95		KLK4_HUMAN (21-254): 2.09e-52: 172: 38.30
+	Mm
		398352 UFO_MOUSE (1062-1348): 4.12e-57: 216: 41.14		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40
+	Mm
		398306 PLXA1_MOUSE (382-925): 4.37e-42: 171: 21.31		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40
+	Mm
		74670 PLXB2_MOUSE (500-796): 2.24e-23: 110: 24.60		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40