HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: AKT3 (Q9Y243)
RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)
Gene: AKT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 479
+	Hs
		248675 PEPL_HUMAN (13-748): 2.34e-35: 147: 12.35		AKT1_HUMAN (1-477): 0: 563: 82.29
+	Hs
		728275 GRDN_HUMAN (28-703): 1.21e-28: 126: 13.71		AKT1_HUMAN (1-477): 0: 563: 82.29
+	Mm
		728520 GRDN_MOUSE (28-719): 2e-27: 122: 13.23		AKT1_MOUSE (1-477): 0: 566: 82.08
+	Mm
		1210031 GRDN_MOUSE (28-719): 2e-27: 122: 13.23		AKT2_MOUSE (1-479): 0: 560: 75.57
+	Hs
		728631 MYO5A_HUMAN (42-632): 2.16e-24: 112: 15.29		AKT2_HUMAN (1-479): 0: 564: 75.78
+	Hs
		587568 DESP_HUMAN (13-640): 3.04e-22: 105: 14.35		AKT1_HUMAN (1-477): 0: 563: 82.29
+	Hs
		728066 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		AKT1_HUMAN (1-477): 0: 563: 82.29
+	Mm
		728542 PEPL_MOUSE (44-703): 1.04e-11: 71: 10.68		AKT1_MOUSE (1-477): 0: 566: 82.08
+	Hs
		605649 CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00		KAPCA_HUMAN (103-442): 4.67e-147: 425: 40.00
+	Dm
		424690 MYSN_DROME (2-638): 2.86e-24: 111: 10.72		KPC1_DROME (13-476): 9.06e-155: 457: 35.48
+	Hs
		666238 PLEC_HUMAN (12-768): 3.36e-22: 105: 12.58		KPCL_HUMAN (117-476): 9.66e-152: 449: 42.54
+	Hs
		605703 GRDN_HUMAN (28-703): 1.21e-28: 126: 13.71		KAPCA_HUMAN (103-442): 4.67e-147: 425: 40.00
+	Hs
		587626 DESP_HUMAN (13-640): 3.04e-22: 105: 14.35		KPCE_HUMAN (53-473): 1.77e-149: 445: 40.52
+	Hs
		772751 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		KPCE_HUMAN (53-473): 1.77e-149: 445: 40.52
+	Mm
		591067 MYH7_MOUSE (4-602): 7.46e-21: 100: 11.04		KPCE_MOUSE (53-473): 1.44e-149: 445: 39.67
+	Mm
		591040 MYH6_MOUSE (4-620): 2.36e-20: 99.1: 10.90		KPCE_MOUSE (53-473): 1.44e-149: 445: 39.67
+	Hs
		122910 MYH1_HUMAN (4-608): 4.3e-20: 98.3: 11.75		SGK1_HUMAN (102-477): 5.73e-149: 433: 47.48
+	Hs
		605578 MYH10_HUMAN (1-631): 5.25e-22: 104: 9.40		KAPCA_HUMAN (103-442): 4.67e-147: 425: 40.00
+	Hs
		605577 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		KAPCA_HUMAN (103-442): 4.67e-147: 425: 40.00