HitPredict

Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Interactor 2: LAIR1 (Q6GTX8)
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305)
Gene: LAIR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	10903717, 9285412
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 287
+	Hs
		850772 PTN11_HUMAN (1-593): 0: 598: 100.00		KI2L1_HUMAN (17-284): 1.12e-71: 226: 22.14
+	Hs
		850817 PTN11_HUMAN (1-593): 0: 598: 100.00		KI2L3_HUMAN (1-162): 1.19e-37: 137: 21.82
+	Hs
		850865 PTN11_HUMAN (1-593): 0: 598: 100.00		KI3L1_HUMAN (1-154): 3.66e-35: 133: 21.66
+	Hs
		1053733 PTN11_HUMAN (1-593): 0: 598: 100.00		KI2L4_HUMAN (1-162): 1.21e-34: 130: 24.85
+	Mm
		767019 PTN11_MOUSE (1-593): 0: 597: 99.49		LRB4A_MOUSE (21-286): 3.15e-31: 120: 18.22
+	Mm
		767005 PTN11_MOUSE (1-593): 0: 597: 99.49		LIRB3_MOUSE (23-150): 1.22e-16: 81.8: 19.23
+	Mm
		767028 PTN11_MOUSE (1-593): 0: 597: 99.49		Q8K4V6_MOUSE (21-155): 7.95e-16: 79.5: 20.71
+	Hs
		658861 PTPRD_HUMAN (39-522): 1.79e-114: 377: 26.96		KI2L1_HUMAN (17-284): 1.12e-71: 226: 22.14
+	Hs
		1102730 PTPRS_HUMAN (39-522): 1.23e-115: 380: 26.76		LIRB4_HUMAN (1-246): 3.62e-56: 188: 25.59
+	Hs
		658912 PTPRD_HUMAN (39-522): 1.79e-114: 377: 26.96		LIRB4_HUMAN (1-246): 3.62e-56: 188: 25.59
+	Hs
		711139 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		LAIR1_HUMAN (1-287): 2.98e-102: 302: 100.00
+	Mm
		711233 PTN6_MOUSE (2-185): 4.92e-19: 93: 26.94		LAIR1_MOUSE (16-287): 7.44e-74: 228: 40.22
+	Hs
		711055 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		KI2L1_HUMAN (17-284): 1.12e-71: 226: 22.14
+	Hs
		711158 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		LIRB4_HUMAN (1-246): 3.62e-56: 188: 25.59
+	Hs
		711056 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		KI2L3_HUMAN (1-162): 1.19e-37: 137: 21.82
+	Hs
		711057 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		KI3L1_HUMAN (1-154): 3.66e-35: 133: 21.66
+	Mm
		711229 PTN6_MOUSE (2-185): 4.92e-19: 93: 26.94		LRB4A_MOUSE (21-286): 3.15e-31: 120: 18.22
+	Hs
		711153 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		LIRB2_HUMAN (28-150): 1.16e-22: 99.5: 24.00
+	Hs
		268952 PTN6_HUMAN (2-101): 5.81e-19: 92.6: 36.70		LIRB3_HUMAN (28-156): 2.17e-20: 92.6: 22.90
+	Mm
		711220 PTN6_MOUSE (2-185): 4.92e-19: 93: 26.94		LIRB3_MOUSE (23-150): 1.22e-16: 81.8: 19.23