HitPredict

Interactor 1: PTN6 (P29351)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (70Z-SHP) (Hematopoietic cell protein-tyrosine phosphatase) (PTPTY-42) (Protein-tyrosine phosphatase 1C) (PTP-1C) (SH-PTP1) (SHP-1)
Gene: Ptpn6

Interactor 2: LAIR1 (Q8BG84)
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (mLAIR1) (CD antigen CD305)
Gene: LAIR1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25915125
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Mm			1 263
+	Hs
		711139 PTN6_HUMAN (1-595): 0: 621: 94.45		LAIR1_HUMAN (1-263): 6.96e-80: 243: 39.72
+	Hs
		711158 PTN6_HUMAN (1-595): 0: 621: 94.45		LIRB4_HUMAN (21-254): 1.16e-53: 181: 20.30
+	Mm
		711229 PTN6_MOUSE (1-595): 0: 617: 100.00		LRB4A_MOUSE (4-262): 1.01e-33: 126: 13.77
+	Hs
		711056 PTN6_HUMAN (1-595): 0: 621: 94.45		KI2L3_HUMAN (1-136): 3.22e-29: 114: 18.06
+	Hs
		711057 PTN6_HUMAN (1-595): 0: 621: 94.45		KI3L1_HUMAN (1-134): 4.74e-27: 110: 19.86
+	Hs
		711055 PTN6_HUMAN (1-595): 0: 621: 94.45		KI2L1_HUMAN (1-143): 1e-23: 99.9: 15.89
+	Hs
		711159 PTN6_HUMAN (1-595): 0: 621: 94.45		LIRB1_HUMAN (1-144): 7.35e-20: 90.6: 13.42
+	Hs
		711153 PTN6_HUMAN (1-595): 0: 621: 94.45		LIRB2_HUMAN (24-134): 1.23e-19: 89.8: 16.81
+	Hs
		268952 PTN6_HUMAN (1-595): 0: 621: 94.45		LIRB3_HUMAN (22-144): 2.76e-18: 86: 17.83
+	Mm
		711220 PTN6_MOUSE (1-595): 0: 617: 100.00		LIRB3_MOUSE (29-154): 9.82e-15: 75.6: 17.29
+	Hs
		658912 PTPRD_HUMAN (34-516): 5.22e-121: 396: 24.60		LIRB4_HUMAN (21-254): 1.16e-53: 181: 20.30
+	Hs
		1102730 PTPRS_HUMAN (34-516): 7.4e-121: 395: 24.60		LIRB4_HUMAN (21-254): 1.16e-53: 181: 20.30
+	Hs
		658861 PTPRD_HUMAN (34-516): 5.22e-121: 396: 24.60		KI2L1_HUMAN (1-143): 1e-23: 99.9: 15.89
+	Hs
		1053680 PTN11_HUMAN (2-104): 3.47e-24: 108: 43.36		LAIR1_HUMAN (1-263): 6.96e-80: 243: 39.72
+	Mm
		767019 PTN11_MOUSE (2-104): 3.9e-24: 108: 43.36		LRB4A_MOUSE (4-262): 1.01e-33: 126: 13.77
+	Hs
		1053733 PTN11_HUMAN (2-104): 3.47e-24: 108: 43.36		KI2L4_HUMAN (1-143): 1.45e-29: 116: 25.68
+	Hs
		850817 PTN11_HUMAN (2-104): 3.47e-24: 108: 43.36		KI2L3_HUMAN (1-136): 3.22e-29: 114: 18.06
+	Hs
		850865 PTN11_HUMAN (2-104): 3.47e-24: 108: 43.36		KI3L1_HUMAN (1-134): 4.74e-27: 110: 19.86
+	Hs
		850772 PTN11_HUMAN (2-104): 3.47e-24: 108: 43.36		KI2L1_HUMAN (1-143): 1e-23: 99.9: 15.89
+	Mm
		767005 PTN11_MOUSE (2-104): 3.9e-24: 108: 43.36		LIRB3_MOUSE (29-154): 9.82e-15: 75.6: 17.29