HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29991511
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 446
+	Hs
		903234 CHD4_HUMAN (1-1912): 0: 1719: 100.00		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Hs
		1059641 CHD4_HUMAN (1-1912): 0: 1719: 100.00		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		997726 CHD4_HUMAN (1-1912): 0: 1719: 100.00		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		1018507 CHD3_HUMAN (23-1905): 0: 1595: 66.89		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		997695 CHD3_HUMAN (23-1905): 0: 1595: 66.89		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		1018714 CHD3_HUMAN (23-1905): 0: 1595: 66.89		NLE1_HUMAN (338-445): 4.67e-18: 88.1: 13.89
+	Hs
		1083322 CHD5_HUMAN (86-1909): 0: 1584: 71.18		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		997824 CHD5_HUMAN (86-1909): 0: 1584: 71.18		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Dm
		332768 CHDM_DROME (1-1904): 0: 1364: 50.85		CAF1_DROME (62-247): 5.03e-21: 96.6: 10.71
+	Ce
		954000 CHD3_CAEEL (111-1909): 0: 1204: 41.29		LIN53_CAEEL (41-247): 1.86e-21: 97.7: 10.33
+	Ce
		104626 LE418_CAEEL (85-1903): 0: 1182: 39.96		LIN53_CAEEL (41-247): 1.86e-21: 97.7: 10.33
+	Hs
		903535 CHD8_HUMAN (489-1678): 0: 752: 28.31		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Sc
		697383 CHD1_YEAST (515-1383): 0: 777: 35.17		TAF5_YEAST (250-445): 1.54e-31: 129: 16.75
+	Hs
		997936 CHD7_HUMAN (3-1678): 0: 805: 23.02		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		229413 SMCA5_HUMAN (578-1624): 0: 791: 26.01		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		229377 SMCA5_HUMAN (578-1624): 0: 791: 26.01		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		658682 SMCA1_HUMAN (617-1597): 0: 779: 27.44		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		658658 SMCA1_HUMAN (617-1597): 0: 779: 27.44		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Dm
		1097621 ISWI_DROME (622-1638): 0: 770: 25.77		CAF1_DROME (62-247): 5.03e-21: 96.6: 10.71
+	Ce
		784763 ISW1_CAEEL (596-1624): 0: 722: 24.50		LIN53_CAEEL (41-247): 1.86e-21: 97.7: 10.33