HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: Q8IPP3 (Q8IPP3)
Canoe, isoform D
Gene: cno

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 1817
+	Hs
		936290 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		AFAD_HUMAN (1-1302): 0: 713: 39.12
+	Hs
		463423 LYN_HUMAN (3-199): 4e-35: 131: 25.24		AFAD_HUMAN (1-1302): 0: 713: 39.12
+	Hs
		557191 SRC_HUMAN (4-208): 1.27e-32: 124: 25.65		AFAD_HUMAN (1-1302): 0: 713: 39.12
+	Hs
		440259 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		MYO5A_HUMAN (82-962): 5.93e-137: 472: 13.34
+	Hs
		840995 ABL2_HUMAN (4-138): 3.24e-23: 98.6: 35.71		MYO5A_HUMAN (82-962): 5.93e-137: 472: 13.34
+	Hs
		987865 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		RADIL_HUMAN (235-1022): 6.7e-73: 268: 14.33
+	Hs
		987931 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		KI13A_HUMAN (247-705): 8.55e-56: 217: 16.02
+	Hs
		987881 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		NEB2_HUMAN (995-1109): 2.46e-30: 132: 37.82
+	Hs
		987771 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		LNX2_HUMAN (981-1093): 5.5e-18: 92.3: 25.86
+	Mm
		1221224 GRB2_MOUSE (1-210): 5.92e-63: 196: 63.08		DLG4_MOUSE (1002-1100): 1.14e-16: 88.3: 32.32
+	Hs
		987532 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		DLG4_HUMAN (1002-1100): 1.14e-16: 88.3: 32.32
+	Dm
		118747 ABL_DROME (4-180): 1.06e-39: 146: 32.24		M9NFI9_DROME (995-1169): 2.39e-29: 130: 27.53
+	Hs
		463837 LYN_HUMAN (3-199): 4e-35: 131: 25.24		NEB1_HUMAN (995-1109): 2.52e-29: 129: 36.98
+	Hs
		463488 LYN_HUMAN (3-199): 4e-35: 131: 25.24		DLG1_HUMAN (890-1280): 9.41e-26: 118: 15.87
+	Hs
		440052 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		DLG1_HUMAN (890-1280): 9.41e-26: 118: 15.87
+	Mm
		440284 LCK_MOUSE (3-200): 6.79e-32: 122: 26.07		DLG1_MOUSE (890-1103): 1.52e-25: 117: 19.27
+	Hs
		463486 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PTN13_HUMAN (918-1422): 3.73e-21: 103: 10.87
+	Hs
		440050 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		PTN13_HUMAN (918-1422): 3.73e-21: 103: 10.87
+	Mm
		431355 SRC_MOUSE (4-208): 1.13e-32: 125: 26.09		DLG4_MOUSE (1002-1100): 1.14e-16: 88.3: 32.32
+	Rn
		723904 SRC_RAT (4-208): 9.1e-33: 125: 25.65		DLG4_RAT (1002-1100): 1.14e-16: 88.3: 32.32