Interactor 1: ULA1 (Q12059)
NEDD8-activating enzyme E1 regulatory subunit (E1 N-terminus-related protein 2) (Ubiquitin-activating enzyme E1-like 1) (Ubiquitin-like activation protein 1)
Gene: ULA1
Interactor 2: UBA3 (Q99344)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (RUB1-activating enzyme E1) (Ubiquitin-activating enzyme E1 3) (Ubiquitin-like protein-activating enzyme)
Gene: UBA3
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.60 | 0.749 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11805826, 11283351, 10688190, 16429126, 9545234, 18719252, 20826334 |
| Identification Methods | tandem affinity purification, two hybrid pooling approach, two hybrid, affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0019781 - NEDD8 activating enzyme activity GO:0045116 - protein neddylation GO:0120123 - ubiquitin activating enzyme complex |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
