HitPredict

Interactor 1: FOXO1 (Q12778)
Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)
Gene: FOXO1

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18815134
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 655 Hs			1 731
+	Hs
		1023212 FOXO4_HUMAN (3-636): 4.29e-37: 147: 32.97		COP1_HUMAN (1-731): 0: 538: 100.00
+	Mm
		1240622 Q6P1H7_MOUSE (83-648): 2.68e-42: 165: 16.64		FBXW7_MOUSE (390-730): 1.97e-83: 280: 16.33
+	Hs
		1061607 FOXM1_HUMAN (30-648): 3.96e-42: 164: 16.67		FBXW7_HUMAN (390-730): 3.04e-83: 280: 16.33
+	Hs
		190082 FOXP2_HUMAN (9-356): 5.58e-41: 161: 15.39		FBXW7_HUMAN (390-730): 3.04e-83: 280: 16.33
+	Mm
		965395 KMT2C_MOUSE (54-616): 5.89e-47: 181: 12.02		WDR5_MOUSE (297-625): 1.46e-64: 219: 16.32
+	Hs
		937689 FOXA1_HUMAN (31-441): 8.04e-43: 162: 16.47		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Hs
		219673 FOXO3_HUMAN (4-655): 1.04e-89: 294: 39.00		TAF5L_HUMAN (486-667): 2.49e-11: 68.9: 29.57
+	Hs
		937728 FOXA1_HUMAN (31-441): 8.04e-43: 162: 16.47		RBBP4_HUMAN (512-702): 3.24e-20: 96: 14.49
+	Hs
		1029664 FOXK2_HUMAN (15-552): 1.6e-40: 159: 17.77		RBBP4_HUMAN (512-702): 3.24e-20: 96: 14.49
+	Dm
		1175600 FOXO_DROME (88-470): 6.93e-40: 156: 32.74		CAF1_DROME (512-702): 1.78e-20: 96.7: 14.02
+	Hs
		1017427 FOXK1_HUMAN (15-550): 2.71e-43: 168: 15.78		RBBP7_HUMAN (476-629): 3.9e-12: 70.9: 29.34
+	Hs
		1091111 FOXC1_HUMAN (120-282): 1.06e-43: 167: 31.33		RBBP7_HUMAN (476-629): 3.9e-12: 70.9: 29.34
+	Hs
		1029686 FOXK2_HUMAN (15-552): 1.6e-40: 159: 17.77		RBBP7_HUMAN (476-629): 3.9e-12: 70.9: 29.34
+	Hs
		1091139 FOXC1_HUMAN (120-282): 1.06e-43: 167: 31.33		SNR40_HUMAN (308-447): 1.62e-09: 62.2: 12.08