HitPredict

Interactor 1: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.696

The method score is based on:

Property Details
Experiments 22908229, 20620956, 21148070, 16543236
Identification Methods affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription
and 8 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 826
Hs

1 832
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024