HitPredict

Interactor 1: LRFN1 (Q2WF71)
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2) (Synaptic differentiation-enhancing molecule 1)
Gene: LRFN1

Interactor 2: DLG1 (Q811D0)
Disks large homolog 1 (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97) (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	16495444
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0098839 - postsynaptic density membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 766 Mm			1 905
+	Mm
		1193431 LRFN2_MOUSE (5-109): 2.88e-14: 78.9: 14.82		DLG1_MOUSE (1-905): 0: 726: 100.00
+	Rn
		1115171 LRFN2_RAT (5-109): 2.08e-14: 79.3: 14.82		DLG1_RAT (1-905): 0: 710: 95.83
+	Mm
		936185 LRC4C_MOUSE (2-367): 8.66e-22: 102: 13.83		DLG3_MOUSE (113-905): 0: 551: 66.26
+	Rn
		1115172 LRFN2_RAT (5-109): 2.08e-14: 79.3: 14.82		DLG3_RAT (113-905): 0: 551: 66.02
+	Mm
		936183 LRFN2_MOUSE (5-109): 2.88e-14: 78.9: 14.82		DLG3_MOUSE (113-905): 0: 551: 66.26
+	Mm
		1103492 LRFN1_MOUSE (1-766): 4.33e-139: 430: 100.00		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Mm
		471547 LRC4B_MOUSE (5-150): 2.05e-24: 111: 19.30		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Mm
		1143410 LRC4C_MOUSE (2-367): 8.66e-22: 102: 13.83		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Mm
		524114 CNTN1_MOUSE (215-644): 1.68e-14: 79.7: 13.26		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Mm
		1143368 LRFN2_MOUSE (5-109): 2.88e-14: 78.9: 14.82		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Rn
		677783 LRFN2_RAT (5-109): 2.08e-14: 79.3: 14.82		DLG4_RAT (32-431): 1.04e-30: 131: 16.50
+	Mm
		1143377 LRFN4_MOUSE (678-759): 9.55e-10: 63.9: 11.24		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Mm
		1207544 LRC4C_MOUSE (2-367): 8.66e-22: 102: 13.83		DLG2_MOUSE (384-810): 3.48e-18: 91.8: 16.74
+	Hs
		1162226 LRFN4_HUMAN (678-759): 7.37e-10: 64.3: 10.11		PALS1_HUMAN (219-407): 1.25e-11: 70.6: 12.63