HitPredict

Interactor 1: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Interactor 2: UBE3B (Q7Z3V4)
Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B)
Gene: UBE3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	37783786
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HECT~UQ_con
Common GO terms	GO:0000209 - protein polyubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 1068
+	Hs
		1154272 UB2V2_HUMAN (4-147): 9.57e-72: 213: 88.89		UBE3B_HUMAN (1-1068): 0: 1413: 100.00
+	Hs
		906670 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		UBE3C_HUMAN (6-1068): 0: 579: 25.55
+	Hs
		982191 UB2D2_HUMAN (12-146): 7.46e-58: 178: 22.96		UBE3C_HUMAN (6-1068): 0: 579: 25.55
+	Hs
		861524 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		NEDD4_HUMAN (604-1066): 1.86e-158: 505: 28.54
+	Hs
		1394641 UB2D4_HUMAN (12-146): 2.62e-59: 181: 24.44		ITCH_HUMAN (604-1066): 1.36e-161: 502: 28.02
+	Hs
		861552 UB2D2_HUMAN (12-146): 7.46e-58: 178: 22.96		NEDD4_HUMAN (604-1066): 1.86e-158: 505: 28.54
+	Hs
		906748 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		ITCH_HUMAN (604-1066): 1.36e-161: 502: 28.02
+	Hs
		906753 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		NED4L_HUMAN (604-1066): 8.59e-159: 497: 27.68
+	Hs
		131839 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		WWP2_HUMAN (655-1066): 6.27e-159: 494: 29.30
+	Hs
		132395 UB2D4_HUMAN (12-146): 2.62e-59: 181: 24.44		WWP2_HUMAN (655-1066): 6.27e-159: 494: 29.30
+	Hs
		131913 UB2D2_HUMAN (12-146): 7.46e-58: 178: 22.96		WWP2_HUMAN (655-1066): 6.27e-159: 494: 29.30
+	Sc
		815511 MMS2_YEAST (10-145): 1.53e-61: 187: 50.00		RSP5_YEAST (604-1066): 8.15e-154: 479: 27.31
+	Hs
		906781 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		WWP1_HUMAN (615-1066): 2.41e-153: 481: 26.71
+	Hs
		906689 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		HUWE1_HUMAN (608-1068): 7.3e-141: 471: 30.02
+	Hs
		906789 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		SMUF1_HUMAN (641-1065): 1.04e-150: 469: 27.64
+	Sp
		153856 UBC4_SCHPO (12-146): 8.79e-58: 178: 23.70		PUB3_SCHPO (592-1066): 2.5e-151: 471: 27.25
+	Hs
		906788 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		SMUF2_HUMAN (646-1065): 1.31e-150: 468: 27.25
+	Hs
		982224 UB2D2_HUMAN (12-146): 7.46e-58: 178: 22.96		HUWE1_HUMAN (608-1068): 7.3e-141: 471: 30.02
+	Hs
		906687 UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27		HECW1_HUMAN (678-1067): 4.14e-46: 183: 33.08
+	Hs
		982221 UB2D2_HUMAN (12-146): 7.46e-58: 178: 22.96		HECW1_HUMAN (678-1067): 4.14e-46: 183: 33.08