HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: CCBE1 (Q6UXH8)
Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog)
Gene: CCBE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 406
+	Hs
		551784 CUL3_HUMAN (1-768): 0: 943: 100.00		CO6A1_HUMAN (147-404): 6.11e-33: 133: 16.81
+	Hs
		133023 CUL3_HUMAN (1-768): 0: 943: 100.00		MATN2_HUMAN (5-222): 8.05e-28: 117: 19.91
+	Hs
		1113071 CUL3_HUMAN (1-768): 0: 943: 100.00		NID2_HUMAN (3-258): 2.57e-26: 113: 20.14
+	Hs
		654497 CUL3_HUMAN (1-768): 0: 943: 100.00		FBLN1_HUMAN (7-248): 3.14e-20: 94.8: 18.92
+	Hs
		1086393 CUL3_HUMAN (1-768): 0: 943: 100.00		FBLN3_HUMAN (67-261): 1.42e-19: 92.5: 19.60
+	Hs
		1113097 CUL3_HUMAN (1-768): 0: 943: 100.00		GAS6_HUMAN (78-264): 4.3e-19: 91.4: 19.69
+	Hs
		572687 CUL3_HUMAN (1-768): 0: 943: 100.00		NID1_HUMAN (16-244): 1.54e-16: 83.9: 12.97
+	Hs
		1113101 CUL3_HUMAN (1-768): 0: 943: 100.00		FAT1_HUMAN (127-308): 5.95e-15: 79.1: 15.85
+	Hs
		878024 CUL3_HUMAN (1-768): 0: 943: 100.00		AGRE5_HUMAN (96-305): 6.71e-14: 75.6: 17.41
+	Hs
		666724 CUL3_HUMAN (1-768): 0: 943: 100.00		TENA_HUMAN (98-312): 2.14e-13: 74.5: 11.20
+	Hs
		1022607 CUL3_HUMAN (1-768): 0: 943: 100.00		LRP2_HUMAN (98-174): 5.52e-12: 70.1: 42.86
+	Hs
		772311 CUL3_HUMAN (1-768): 0: 943: 100.00		FBN2_HUMAN (43-177): 1.2e-10: 65.8: 17.62
+	Hs
		1113122 CUL3_HUMAN (1-768): 0: 943: 100.00		LTBP1_HUMAN (11-235): 2.49e-10: 64.7: 13.62
+	Hs
		183248 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMA5_HUMAN (5-200): 4.07e-10: 64.1: 10.10
+	Hs
		673767 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMA1_HUMAN (2-144): 6.79e-10: 63.3: 10.98
+	Hs
		317567 CUL3_HUMAN (1-768): 0: 943: 100.00		SLIT2_HUMAN (2-124): 2.15e-09: 61.8: 16.80
+	Hs
		471589 CUL3_HUMAN (1-768): 0: 943: 100.00		CO4A2_HUMAN (246-329): 2.63e-09: 61.2: 47.62
+	Hs
		438030 CUL3_HUMAN (1-768): 0: 943: 100.00		CO5A2_HUMAN (246-333): 4.76e-09: 60.5: 47.83
+	Hs
		384313 CUL3_HUMAN (1-768): 0: 943: 100.00		CO4A1_HUMAN (245-337): 7.05e-09: 60.1: 46.08
+	Hs
		772280 CUL3_HUMAN (1-768): 0: 943: 100.00		FBN1_HUMAN (43-206): 9.59e-09: 59.6: 15.66