HitPredict

Interactor 1: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030054 - cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1128 Hs			1 779
+	Hs
		1115527 ASPP2_HUMAN (1-1128): 0: 588: 100.00		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		1197057 ASPP1_HUMAN (1-1128): 1.03e-130: 427: 45.38		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		1115622 ASPP2_HUMAN (1-1128): 0: 588: 100.00		CING_HUMAN (175-776): 1.72e-17: 89.7: 9.97
+	Hs
		1115623 ASPP2_HUMAN (1-1128): 0: 588: 100.00		EP15R_HUMAN (483-673): 1.1e-10: 67.4: 13.09
+	Hs
		1115515 ASPP2_HUMAN (1-1128): 0: 588: 100.00		PLEC_HUMAN (191-769): 1.21e-09: 64.3: 9.88
+	Hs
		86313 Q05BL1_HUMAN (91-1128): 2.69e-149: 476: 100.00		B9EK46_HUMAN (175-776): 1.73e-17: 89.7: 9.97
+	Hs
		1396272 ASPP1_HUMAN (1-1128): 1.03e-130: 427: 45.38		CING_HUMAN (175-776): 1.72e-17: 89.7: 9.97
+	Hs
		86314 ASPP1_HUMAN (1-1128): 1.03e-130: 427: 45.38		B9EK46_HUMAN (175-776): 1.73e-17: 89.7: 9.97
+	Hs
		1197085 TNKS2_HUMAN (827-1127): 1.75e-41: 168: 11.11		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		1432028 TNKS2_HUMAN (827-1127): 1.75e-41: 168: 11.11		AMOL2_HUMAN (1-779): 8.18e-72: 252: 100.00
+	Hs
		177233 ANR28_HUMAN (781-1114): 1.35e-41: 168: 12.75		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		1197020 ANR52_HUMAN (860-1075): 1.94e-33: 142: 13.24		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		270853 DAPLE_HUMAN (128-937): 1.96e-85: 307: 14.52		ROCK2_HUMAN (307-656): 3.35e-12: 72.4: 18.06
+	Hs
		1314103 TNKS2_HUMAN (827-1127): 1.75e-41: 168: 11.11		AMOL1_HUMAN (1-766): 2.7e-42: 168: 40.22
+	Hs
		1154105 ANR54_HUMAN (902-1045): 1.28e-39: 151: 31.97		ITSN1_HUMAN (136-766): 1.51e-36: 150: 11.46
+	Hs
		177343 ANR28_HUMAN (781-1114): 1.35e-41: 168: 12.75		SMC3_HUMAN (220-710): 6.51e-09: 61.6: 14.34
+	Hs
		1143211 CTTB2_HUMAN (513-1127): 7.92e-23: 108: 11.20		PLEC_HUMAN (191-769): 1.21e-09: 64.3: 9.88
+	Hs
		1433475 Q9H4D1_HUMAN (795-1024): 1e-23: 110: 16.88		SMC3_HUMAN (220-710): 6.51e-09: 61.6: 14.34
+	Hs
		944102 RIPK4_HUMAN (795-1024): 1.2e-23: 109: 16.45		SMC3_HUMAN (220-710): 6.51e-09: 61.6: 14.34
+	Hs
		270834 ANR49_HUMAN (906-1000): 8.89e-19: 88.7: 30.53		ROCK2_HUMAN (307-656): 3.35e-12: 72.4: 18.06