Interactor 1: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 33961781, 35271311, 37689310, 19615732
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 565
Hs

1 357
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Last updated: 15 Jul 2024