HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: ANR54 (Q6NXT1)
Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein)
Gene: ANKRD54

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_9
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 300
+	Hs
		920441 SRC8_HUMAN (1-550): 0: 561: 100.00		DAPK1_HUMAN (103-298): 4.2e-39: 147: 19.19
+	Hs
		1091395 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		ANK3_HUMAN (83-297): 5.97e-61: 211: 20.31
+	Hs
		1030639 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		ANK2_HUMAN (82-297): 7.24e-60: 208: 19.62
+	Mm
		597663 SPTN1_MOUSE (213-549): 6.82e-34: 139: 14.12		ANK2_MOUSE (82-297): 7.23e-60: 208: 19.62
+	Mm
		86327 B9EKJ1_MOUSE (213-549): 5.53e-34: 140: 14.12		ANK3_MOUSE (83-297): 2e-57: 201: 20.31
+	Hs
		943926 MYO1E_HUMAN (165-549): 9.91e-45: 172: 15.01		RIPK4_HUMAN (1-173): 1.96e-42: 157: 15.64
+	Hs
		1091715 MYO1E_HUMAN (165-549): 9.91e-45: 172: 15.01		Q9H4D1_HUMAN (1-173): 4.03e-42: 156: 15.64
+	Hs
		1091730 MYO1E_HUMAN (165-549): 9.91e-45: 172: 15.01		ANR50_HUMAN (124-297): 3.28e-39: 148: 21.17
+	Hs
		1154105 ITSN1_HUMAN (165-548): 6.15e-15: 80.5: 11.99		ANR54_HUMAN (11-300): 2.7e-68: 216: 100.00
+	Hs
		250271 VINEX_HUMAN (254-546): 4.07e-13: 73.9: 13.51		ANR54_HUMAN (11-300): 2.7e-68: 216: 100.00
+	Hs
		920439 SPTN1_HUMAN (213-549): 8.25e-34: 139: 14.12		DAPK1_HUMAN (103-298): 4.2e-39: 147: 19.19
+	Mm
		109257 ABI2_MOUSE (332-547): 9.93e-13: 72.1: 20.72		ANK3_MOUSE (83-297): 2e-57: 201: 20.31
+	Hs
		177302 SH3G3_HUMAN (365-549): 5.48e-31: 125: 18.82		ANR28_HUMAN (1-164): 2.96e-27: 113: 16.57
+	Hs
		944018 STAM1_HUMAN (416-546): 2.83e-13: 74.4: 21.83		RIPK4_HUMAN (1-173): 1.96e-42: 157: 15.64
+	Hs
		1368301 STAM1_HUMAN (416-546): 2.83e-13: 74.4: 21.83		Q9H4D1_HUMAN (1-173): 4.03e-42: 156: 15.64
+	Hs
		274251 ITSN2_HUMAN (398-548): 1.25e-18: 92.3: 17.88		ANR17_HUMAN (1-102): 8.13e-18: 86: 12.15