HitPredict

Interactor 1: ZMY11 (Q15326)
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)
Gene: ZMYND11

Interactor 2: EZH1 (Q92800)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16565076
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 602 Hs			1 747
+	Hs
		1146232 ZMY11_HUMAN (1-602): 0: 608: 100.00		EZH2_HUMAN (8-746): 0: 719: 62.78
+	Hs
		1155907 TRI33_HUMAN (57-304): 6.51e-41: 161: 16.67		EZH2_HUMAN (8-746): 0: 719: 62.78
+	Hs
		1155721 CECR2_HUMAN (123-470): 3.43e-39: 156: 12.26		EZH2_HUMAN (8-746): 0: 719: 62.78
+	Hs
		1155617 KAT2B_HUMAN (122-254): 2.58e-31: 131: 17.78		EZH2_HUMAN (8-746): 0: 719: 62.78
+	Hs
		1099935 TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29		EZH2_HUMAN (8-746): 0: 719: 62.78
+	Hs
		1155592 PHIP_HUMAN (123-555): 1.23e-23: 108: 10.97		EZH2_HUMAN (8-746): 0: 719: 62.78
+	Hs
		1041531 ZMY11_HUMAN (1-602): 0: 608: 100.00		KMT2A_HUMAN (620-734): 4.38e-19: 95.1: 42.24
+	Hs
		174607 TRI66_HUMAN (75-309): 1.81e-43: 169: 18.35		SETD2_HUMAN (181-733): 4.67e-76: 270: 14.90
+	Dm
		567654 FSH_DROME (128-259): 2.77e-29: 126: 15.56		ASH1_DROME (180-733): 3.4e-88: 306: 17.04
+	Hs
		1416765 CECR2_HUMAN (123-470): 3.43e-39: 156: 12.26		SETD2_HUMAN (181-733): 4.67e-76: 270: 14.90
+	Hs
		1419385 BRPF3_HUMAN (127-549): 1.44e-38: 154: 14.13		SETD2_HUMAN (181-733): 4.67e-76: 270: 14.90
+	Hs
		216427 TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29		SUV91_HUMAN (422-732): 3.17e-81: 266: 22.98
+	Hs
		1369197 KAT2B_HUMAN (122-254): 2.58e-31: 131: 17.78		EHMT2_HUMAN (419-733): 8.15e-74: 262: 23.10
+	Hs
		1100249 TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29		EHMT2_HUMAN (419-733): 8.15e-74: 262: 23.10
+	Hs
		1100395 TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29		EHMT1_HUMAN (416-733): 2.13e-73: 261: 21.88
+	Hs
		1447966 BRPF3_HUMAN (127-549): 1.44e-38: 154: 14.13		ASH1L_HUMAN (547-733): 1.61e-54: 206: 31.75
+	Hs
		355514 TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29		NSD2_HUMAN (471-730): 3.9e-61: 225: 24.09
+	Sc
		863944 GCN5_YEAST (128-256): 7.26e-33: 133: 16.15		SET2_YEAST (547-734): 3.25e-54: 201: 32.11
+	Hs
		175883 TIF1B_HUMAN (76-254): 7.98e-31: 130: 14.29		SET1A_HUMAN (612-733): 1.13e-18: 93.6: 39.52
+	Hs
		639717 TAF1_HUMAN (129-459): 8.78e-25: 112: 12.20		KMT2A_HUMAN (620-734): 4.38e-19: 95.1: 42.24