HitPredict

Interactor 1: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Interactor 2: ZNRF1 (Q8ND25)
E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283 protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1)
Gene: ZNRF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 145 Hs			1 227
+	Hs
		1336243 UB2D4_HUMAN (10-144): 7.14e-60: 183: 24.27		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		906709 UB2D1_HUMAN (10-145): 1.75e-59: 182: 24.82		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		982250 UB2D2_HUMAN (10-144): 2.48e-58: 179: 22.06		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		957136 UB2D3_HUMAN (10-144): 8.08e-58: 178: 22.06		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		1336239 UB2E3_HUMAN (2-143): 1.39e-56: 177: 23.08		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		1336242 UB2E2_HUMAN (2-143): 1.75e-56: 176: 23.08		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		909353 UB2E1_HUMAN (1-143): 4.6e-56: 175: 22.92		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		1103918 UB2V1_HUMAN (3-145): 3.15e-55: 171: 89.51		ZNRF1_HUMAN (1-227): 1.18e-130: 369: 100.00
+	Hs
		1338045 UB2D4_HUMAN (10-144): 7.14e-60: 183: 24.27		Q8NEX1_HUMAN (46-227): 8.15e-77: 231: 50.55
+	Hs
		906710 UB2D1_HUMAN (10-145): 1.75e-59: 182: 24.82		Q8NEX1_HUMAN (46-227): 8.15e-77: 231: 50.55
+	Hs
		982251 UB2D2_HUMAN (10-144): 2.48e-58: 179: 22.06		Q8NEX1_HUMAN (46-227): 8.15e-77: 231: 50.55
+	Hs
		957137 UB2D3_HUMAN (10-144): 8.08e-58: 178: 22.06		Q8NEX1_HUMAN (46-227): 8.15e-77: 231: 50.55
+	Hs
		1340074 UB2D4_HUMAN (10-144): 7.14e-60: 183: 24.27		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		906711 UB2D1_HUMAN (10-145): 1.75e-59: 182: 24.82		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		982253 UB2D2_HUMAN (10-144): 2.48e-58: 179: 22.06		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		957140 UB2D3_HUMAN (10-144): 8.08e-58: 178: 22.06		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		1340065 UB2E3_HUMAN (2-143): 1.39e-56: 177: 23.08		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		1340067 UB2E2_HUMAN (2-143): 1.75e-56: 176: 23.08		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		909354 UB2E1_HUMAN (1-143): 4.6e-56: 175: 22.92		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72
+	Hs
		1103920 UB2V1_HUMAN (3-145): 3.15e-55: 171: 89.51		ZNRF2_HUMAN (51-227): 9.88e-74: 225: 49.72