Protein: UB2V1
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)

Gene: UB2V1, UBE2V1
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q13404

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957728

UBE2N
Ubiquitin-conjugating enzyme E2 N

21

16

Small-scale

0.990

High

1103949

TRAF6
TNF receptor-associated factor 6

11

20

Small-scale

0.976

High

241591

PRKN
E3 ubiquitin-protein ligase parkin

5

20

Small-scale

0.930

High

1103945

UBQL1
Ubiquilin-1

4

11

High-throughput

0.907

High

1093345

TRI32
E3 ubiquitin-protein ligase TRIM32

4

20

Small-scale

0.906

High

1103946

CHIP
E3 ubiquitin-protein ligase CHIP

4

15

Small-scale

0.903

High

507924

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

20

Small-scale

0.845

High

1103944

UBQL2
Ubiquilin-2

2

11

High-throughput

0.783

High

1103897

BIRC3
Baculoviral IAP repeat-containing protein 3

2

20

Small-scale

0.778

High

1103948

RNF11
RING finger protein 11

2

20

Small-scale

0.776

High

623324

RO52
E3 ubiquitin-protein ligase TRIM21

2

20

Small-scale

0.768

High

186543

TRI18
E3 ubiquitin-protein ligase Midline-1

1

20

High-throughput

0.698

High

322557

RNF37
RING finger protein 37

1

6

High-throughput

0.698

High

335118

ARI2
E3 ubiquitin-protein ligase ARIH2

1

20

High-throughput

0.698

High

898229

R144A
E3 ubiquitin-protein ligase RNF144A

1

20

High-throughput

0.698

High

1022704

XIAP
E3 ubiquitin-protein ligase XIAP

1

20

High-throughput

0.698

High

1093614

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

16

High-throughput

0.698

High

1103910

RN111
E3 ubiquitin-protein ligase Arkadia

1

20

High-throughput

0.698

High

1103913

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

20

High-throughput

0.698

High

1103915

RNF10
E3 ubiquitin-protein ligase RNF10

1

20

High-throughput

0.698

High

1103916

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

20

High-throughput

0.698

High

1103918

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

1

20

High-throughput

0.698

High

1103930

BIRC8
Baculoviral IAP repeat-containing protein 8

1

20

High-throughput

0.698

High

1103931

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.698

High

1103933

RNF5
E3 ubiquitin-protein ligase RNF5

1

20

High-throughput

0.698

High

1103935

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

20

High-throughput

0.698

High

1103936

TRIM5
Tripartite motif-containing protein 5

1

20

High-throughput

0.698

High

1103942

RNF14
E3 ubiquitin-protein ligase RNF14

1

20

High-throughput

0.698

High

1103906

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

16

High-throughput

0.691

High

1103926

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

3

5

Small-scale

0.655

High

1090623

TRAF2
TNF receptor-associated factor 2

1

20

Small-scale

0.647

High

1103898

BIRC2
Baculoviral IAP repeat-containing protein 2

1

20

Small-scale

0.647

High

1103901

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

20

Small-scale

0.647

High

1103912

UBE3B
Ubiquitin-protein ligase E3B

1

20

Small-scale

0.647

High

1103940

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

20

Small-scale

0.647

High

1103927

OTUB1
Ubiquitin thioesterase OTUB1

1

9

Small-scale

0.646

High

1103928

RN185
E3 ubiquitin-protein ligase RNF185

1

20

High-throughput

0.625

High

1103920

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

20

Small-scale

0.621

High

647549

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

20

Small-scale

0.618

High

1103899

CUL4A
Cullin-4A

1

16

High-throughput

0.618

High

1103908

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

20

Small-scale

0.618

High

1103917

RN149
E3 ubiquitin-protein ligase RNF149

1

20

High-throughput

0.618

High

1103919

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.618

High

608971

XBP1
X-box-binding protein 1

2

2

High-throughput

0.606

High

1103903

DAZP2
DAZ-associated protein 2

2

3

High-throughput

0.606

High

138095

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

4

Small-scale

0.595

High

109398

G5E9A7
DM1 locus, WD repeat containing

1

15

High-throughput

0.594

High

1006244

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.580

High

1103941

TRI39
E3 ubiquitin-protein ligase TRIM39

1

20

High-throughput

0.541

High

999347

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.536

High

999634

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.536

High

1103932

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.536

High

1103947

MINP1
Multiple inositol polyphosphate phosphatase 1

1

1

High-throughput

0.536

High

245929

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.515

High

384409

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.515

High

442312

GELS
Gelsolin

1

2

High-throughput

0.515

High

535019

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.515

High

927277

ATX1
Ataxin-1

1

4

High-throughput

0.515

High

1095983

TADBP
TAR DNA-binding protein 43

1

5

High-throughput

0.515

High

1103924

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

1103904

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1098780

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

13

Small-scale

0.501

High

1103907

RC3H1
Roquin-1

1

11

Small-scale

0.501

High

1103914

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

5

Small-scale

0.501

High

1103939

RC3H2
Roquin-2

1

14

Small-scale

0.501

High

1103923

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

225412

CIKS
E3 ubiquitin ligase TRAF3IP2

1

0

Small-scale

0.480

High

538954

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

606722

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

822648

VHL
von Hippel-Lindau disease tumor suppressor

1

4

High-throughput

0.479

High

872295

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.479

High

934564

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

1097185

PAK2
Serine/threonine-protein kinase PAK 2

1

2

High-throughput

0.479

High

1103900

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

10

High-throughput

0.479

High

1103911

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1103922

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

1103937

LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1

1

2

High-throughput

0.479

High

1103943

ZRAN1
Ubiquitin thioesterase ZRANB1

1

16

High-throughput

0.479

High

650149

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.470

High

1103902

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

2

High-throughput

0.470

High

588612

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

695371

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

768105

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

1103929

EGLN2
Prolyl hydroxylase EGLN2

1

0

Small-scale

0.458

High

685184

PAX6
Paired box protein Pax-6

1

1

High-throughput

0.445

High

691731

MK03
Mitogen-activated protein kinase 3

1

2

High-throughput

0.445

High

776810

MYH11
Myosin-11

1

1

High-throughput

0.445

High

986396

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.445

High

1103934

ERP44
Endoplasmic reticulum resident protein 44

1

4

High-throughput

0.445

High

1103938

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

353308

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

1103921

F168A
Protein FAM168A

2

0

High-throughput

0.327

High

1103925

SHSA4
Protein shisa-4

2

0

High-throughput

0.316

High

1103905

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1103909

RHDF2
Inactive rhomboid protein 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025