HitPredict

Interactor 1: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Interactor 2: AR13B (Q3SXY8)
ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1)
Gene: ARL13B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 100 Hs			1 428
+	Hs
		278505 VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00		AR13B_HUMAN (1-428): 5.18e-137: 401: 100.00
+	Hs
		662348 VAMP1_HUMAN (8-87): 1.97e-25: 93.1: 80.00		AR13B_HUMAN (1-428): 5.18e-137: 401: 100.00
+	Hs
		989340 VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01		AR13B_HUMAN (1-428): 5.18e-137: 401: 100.00
+	Hs
		328677 VAMP5_HUMAN (11-80): 1.65e-20: 80.8: 38.57		AR13B_HUMAN (1-428): 5.18e-137: 401: 100.00
+	Hs
		278487 VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00		ARF6_HUMAN (20-191): 1.31e-76: 237: 29.65
+	Hs
		975054 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		ARF6_HUMAN (20-191): 1.31e-76: 237: 29.65
+	Sc
		536076 SEC22_YEAST (1-97): 4.41e-22: 87.3: 18.56		ARF1_YEAST (5-194): 1.78e-78: 242: 32.63
+	Hs
		907997 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		ARF6_HUMAN (20-191): 1.31e-76: 237: 29.65
+	Sc
		536088 SNC1_YEAST (6-81): 8.84e-22: 83.9: 32.90		ARF1_YEAST (5-194): 1.78e-78: 242: 32.63
+	Hs
		981286 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB1A_HUMAN (22-223): 2.78e-73: 230: 17.87
+	Hs
		974971 VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01		ARF6_HUMAN (20-191): 1.31e-76: 237: 29.65
+	Hs
		975212 VAMP8_HUMAN (6-82): 1.06e-22: 85.8: 35.07		ARF6_HUMAN (20-191): 1.31e-76: 237: 29.65
+	Hs
		1154737 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB1B_HUMAN (22-223): 4.75e-70: 221: 16.91
+	Hs
		908038 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		RAB2B_HUMAN (22-238): 3.24e-69: 220: 14.87
+	Hs
		955934 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		RAB8A_HUMAN (22-221): 2.62e-67: 215: 17.07
+	Sc
		376268 SEC22_YEAST (1-97): 4.41e-22: 87.3: 18.56		YPT1_YEAST (22-223): 3.32e-67: 214: 17.06
+	Hs
		1154765 VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00		ARL8B_HUMAN (1-188): 5.51e-26: 105: 31.41
+	Hs
		908054 VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51		ARL8B_HUMAN (1-188): 5.51e-26: 105: 31.41