Interactor 1: BAK (Q16611)
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)
Gene: BAK1
Interactor 2: B2CL2 (Q92843)
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
Gene: BCL2L2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.927 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 25115399, 10381646, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~Bcl-2, BH4~Bcl-2 |
| Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage and 4 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
