HitPredict

Interactor 1: SP6 (Q3SY56)
Transcription factor Sp6 (Krueppel-like factor 14)
Gene: SP6

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19088080
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 488
+	Hs
		1036894 SP3_HUMAN (225-340): 1.9e-45: 168: 68.97		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		188321 SP7_HUMAN (28-374): 1.56e-98: 301: 37.93		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		267160 SP3_MOUSE (225-340): 7.55e-46: 169: 68.97		HDAC2_MOUSE (1-488): 0: 704: 99.39
+	Hs
		1241433 ZFP1_HUMAN (199-375): 9.76e-47: 165: 17.51		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		465015 SP1_HUMAN (184-375): 1.85e-40: 154: 45.13		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1118746 KLF5_HUMAN (249-337): 4.75e-26: 110: 58.43		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		148630 SP3_MOUSE (225-340): 7.55e-46: 169: 68.97		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		1036874 SP3_HUMAN (225-340): 1.9e-45: 168: 68.97		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		148634 SP1_MOUSE (198-375): 3.98e-41: 155: 48.32		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		464950 SP1_HUMAN (184-375): 1.85e-40: 154: 45.13		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		148717 Q8BPQ2_MOUSE (245-336): 3.08e-26: 108: 56.52		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		1109706 KLF5_HUMAN (249-337): 4.75e-26: 110: 58.43		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		167260 KLF11_HUMAN (256-341): 9.54e-26: 110: 61.63		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		188147 SP1_HUMAN (184-375): 1.85e-40: 154: 45.13		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		313418 SP1_MOUSE (198-375): 3.98e-41: 155: 48.32		Q9JM08_MOUSE (10-431): 0: 568: 58.02
+	Hs
		1281686 ZSCA2_HUMAN (3-314): 2.72e-102: 316: 10.43		HDAC8_HUMAN (33-372): 1.02e-137: 403: 43.40
+	Hs
		188348 KLF6_HUMAN (245-336): 3.49e-27: 110: 56.52		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		1297221 Q8BPQ2_MOUSE (245-336): 3.08e-26: 108: 56.52		Q9JM08_MOUSE (10-431): 0: 568: 58.02
+	Hs
		638603 ZNF10_HUMAN (119-342): 4.26e-53: 186: 14.29		HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04
+	Hs
		1356763 KLF16_HUMAN (254-338): 4.5e-27: 109: 61.18		HDAC7_HUMAN (29-280): 1.97e-23: 106: 26.37