HitPredict

Interactor 1: LMTK2 (Q3TYD6)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Brain-enriched kinase) (Lemur tyrosine kinase 2)
Gene: LMTK2

Interactor 2: RHEB (Q921J2)
GTP-binding protein Rheb (EC 3.6.5.-) (Ras homolog enriched in brain)
Gene: RHEB

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1471 Mm			1 184
+	Hs
		976396 LMTK2_HUMAN (1-1471): 0: 1106: 76.18		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	At
		1184672 M3KE1_ARATH (134-1152): 3.66e-148: 489: 14.14		RAA1B_ARATH (7-175): 1.09e-75: 227: 31.77
+	Hs
		317283 STK10_HUMAN (104-952): 2.54e-130: 430: 16.46		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	Hs
		650172 FGFR3_HUMAN (16-461): 2.41e-115: 384: 20.76		RHEB_HUMAN (1-184): 3.43e-93: 270: 98.91
+	Hs
		541421 FGFR1_HUMAN (16-470): 3.5e-118: 393: 20.49		RAB8A_HUMAN (7-179): 3.21e-85: 251: 29.05
+	Hs
		363098 EGFR_HUMAN (115-599): 6.93e-122: 413: 20.86		RAB1A_HUMAN (4-183): 7.92e-77: 229: 30.27
+	Hs
		363088 EGFR_HUMAN (115-599): 6.93e-122: 413: 20.86		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	Hs
		710801 EPHB2_HUMAN (36-413): 1.27e-120: 406: 23.50		RAB2A_HUMAN (1-173): 9.31e-75: 224: 31.03
+	Hs
		541423 FGFR1_HUMAN (16-470): 3.5e-118: 393: 20.49		RAB1A_HUMAN (4-183): 7.92e-77: 229: 30.27
+	Hs
		541510 FGFR1_HUMAN (16-470): 3.5e-118: 393: 20.49		RB11B_HUMAN (4-182): 3.67e-75: 226: 31.11
+	Hs
		541613 FGFR1_HUMAN (16-470): 3.5e-118: 393: 20.49		RAB2B_HUMAN (1-173): 2.07e-73: 221: 29.89
+	Hs
		710697 EPHA8_HUMAN (5-409): 1.35e-113: 385: 22.49		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	Hs
		956301 EPHA7_HUMAN (53-409): 5.25e-113: 383: 24.44		RAB2A_HUMAN (1-173): 9.31e-75: 224: 31.03
+	Hs
		650320 FGFR3_HUMAN (16-461): 2.41e-115: 384: 20.76		RAB2B_HUMAN (1-173): 2.07e-73: 221: 29.89
+	Hs
		541424 FGFR1_HUMAN (16-470): 3.5e-118: 393: 20.49		RAP1A_HUMAN (5-169): 2.46e-36: 126: 38.55
+	Hs
		411698 NTRK1_HUMAN (130-409): 2.86e-34: 144: 30.98		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	Hs
		439696 INSR_HUMAN (92-406): 6.75e-32: 138: 32.52		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	Hs
		465472 IGF1R_HUMAN (130-398): 5.27e-31: 135: 32.37		RB11A_HUMAN (4-180): 1.1e-75: 227: 30.34
+	Hs
		411703 NTRK1_HUMAN (130-409): 2.86e-34: 144: 30.98		RAP1A_HUMAN (5-169): 2.46e-36: 126: 38.55
+	Hs
		411257 NTRK1_HUMAN (130-409): 2.86e-34: 144: 30.98		RALA_HUMAN (8-166): 6.06e-31: 113: 35.22