HitPredict

Interactor 1: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Interactor 2: RFXK (Q9Z205)
DNA-binding protein RFXANK (Ankyrin repeat-containing adapter protein Tvl-1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: Rfxank

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16236793
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0042826 - histone deacetylase binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1115 Mm			1 269
+	Mm
		1190353 Q3UJF1_MOUSE (1-1115): 0: 778: 100.00		ANRA2_MOUSE (64-261): 4.23e-69: 217: 61.62
+	Hs
		158519 HDAC5_HUMAN (1-1115): 0: 742: 93.42		RFXK_HUMAN (1-269): 1.13e-72: 225: 80.74
+	Hs
		1437027 HDAC5_HUMAN (1-1115): 0: 742: 93.42		ANRA2_HUMAN (64-261): 4.13e-71: 222: 62.12
+	Mm
		1240215 HDAC4_MOUSE (3-1096): 0: 687: 54.65		RFXK_MOUSE (1-269): 1.53e-81: 247: 100.00
+	Hs
		158422 HDAC4_HUMAN (3-1095): 0: 677: 56.10		RFXK_HUMAN (1-269): 1.13e-72: 225: 80.74
+	Hs
		941060 HDAC4_HUMAN (3-1095): 0: 677: 56.10		ANRA2_HUMAN (64-261): 4.13e-71: 222: 62.12
+	Hs
		158516 HDAC9_HUMAN (26-1048): 0: 629: 55.32		RFXK_HUMAN (1-269): 1.13e-72: 225: 80.74
+	Hs
		1437025 HDAC9_HUMAN (26-1048): 0: 629: 55.32		ANRA2_HUMAN (64-261): 4.13e-71: 222: 62.12
+	Mm
		1240023 HDAC4_MOUSE (3-1096): 0: 687: 54.65		TNKS1_MOUSE (93-268): 1.88e-43: 159: 19.40
+	Hs
		158478 HDAC2_HUMAN (686-1112): 5.77e-152: 464: 21.17		RFXK_HUMAN (1-269): 1.13e-72: 225: 80.74
+	Hs
		188368 HDAC3_HUMAN (673-1109): 1.01e-144: 443: 20.92		ANRA2_HUMAN (64-261): 4.13e-71: 222: 62.12
+	Hs
		1110089 HDAC1_HUMAN (666-1100): 2.28e-154: 470: 20.58		EHMT1_HUMAN (5-180): 2.41e-31: 124: 15.00
+	Hs
		1368129 HDAC2_HUMAN (686-1112): 5.77e-152: 464: 21.17		EHMT1_HUMAN (5-180): 2.41e-31: 124: 15.00
+	Hs
		274143 HDAC1_HUMAN (666-1100): 2.28e-154: 470: 20.58		ANR17_HUMAN (3-122): 1.59e-21: 96: 10.66
+	Hs
		274215 HDAC2_HUMAN (686-1112): 5.77e-152: 464: 21.17		ANR17_HUMAN (3-122): 1.59e-21: 96: 10.66
+	Hs
		1311358 HDAC2_HUMAN (686-1112): 5.77e-152: 464: 21.17		ANKH1_HUMAN (3-122): 4.27e-20: 91.8: 9.84
+	Hs
		177211 HDAC1_HUMAN (666-1100): 2.28e-154: 470: 20.58		ANR28_HUMAN (2-154): 1.88e-17: 83.7: 11.95
+	Hs
		1109993 HDAC1_HUMAN (666-1100): 2.28e-154: 470: 20.58		EHMT2_HUMAN (121-238): 9e-13: 70.1: 35.59
+	Hs
		1368057 HDAC2_HUMAN (686-1112): 5.77e-152: 464: 21.17		EHMT2_HUMAN (121-238): 9e-13: 70.1: 35.59