HitPredict

Interactor 1: RFXK (O14593)
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: RFXANK

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	15964851
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042826 - histone deacetylase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 260 Hs			1 1011
+	Hs
		1437025 ANRA2_HUMAN (34-252): 4.83e-73: 227: 57.27		HDAC9_HUMAN (1-1011): 0: 870: 100.00
+	Hs
		158422 RFXK_HUMAN (1-260): 5.97e-85: 255: 100.00		HDAC4_HUMAN (1-1009): 0: 748: 56.07
+	Hs
		941060 ANRA2_HUMAN (34-252): 4.83e-73: 227: 57.27		HDAC4_HUMAN (1-1009): 0: 748: 56.07
+	Mm
		1240215 RFXK_MOUSE (1-260): 5.36e-76: 233: 81.11		HDAC4_MOUSE (1-1009): 0: 734: 55.83
+	Hs
		158519 RFXK_HUMAN (1-260): 5.97e-85: 255: 100.00		HDAC5_HUMAN (1-1008): 0: 674: 56.04
+	Mm
		1190366 RFXK_MOUSE (1-260): 5.36e-76: 233: 81.11		Q3UJF1_MOUSE (1-1008): 0: 672: 55.73
+	Hs
		1437027 ANRA2_HUMAN (34-252): 4.83e-73: 227: 57.27		HDAC5_HUMAN (1-1008): 0: 674: 56.04
+	Mm
		59044 TANC2_MOUSE (5-179): 3.96e-13: 70.8: 13.71		HDAC4_MOUSE (1-1009): 0: 734: 55.83
+	Mm
		1190353 ANRA2_MOUSE (183-259): 1.64e-16: 79.2: 25.97		Q3UJF1_MOUSE (1-1008): 0: 672: 55.73
+	Hs
		158478 RFXK_HUMAN (1-260): 5.97e-85: 255: 100.00		HDAC2_HUMAN (625-1009): 4.6e-135: 417: 22.84
+	Hs
		188368 ANRA2_HUMAN (34-252): 4.83e-73: 227: 57.27		HDAC3_HUMAN (630-1007): 3.09e-134: 413: 22.02
+	Hs
		1109993 EHMT2_HUMAN (61-259): 1.09e-54: 191: 22.28		HDAC1_HUMAN (625-1009): 3.66e-145: 443: 23.35
+	Hs
		1110089 EHMT1_HUMAN (3-171): 5.09e-47: 169: 16.47		HDAC1_HUMAN (625-1009): 3.66e-145: 443: 23.35
+	Hs
		1368057 EHMT2_HUMAN (61-259): 1.09e-54: 191: 22.28		HDAC2_HUMAN (625-1009): 4.6e-135: 417: 22.84
+	Hs
		1368129 EHMT1_HUMAN (3-171): 5.09e-47: 169: 16.47		HDAC2_HUMAN (625-1009): 4.6e-135: 417: 22.84
+	Hs
		177211 ANR28_HUMAN (2-178): 9.21e-37: 139: 18.58		HDAC1_HUMAN (625-1009): 3.66e-145: 443: 23.35
+	Hs
		274143 ANR17_HUMAN (2-127): 2.17e-31: 124: 16.28		HDAC1_HUMAN (625-1009): 3.66e-145: 443: 23.35
+	Hs
		274215 ANR17_HUMAN (2-127): 2.17e-31: 124: 16.28		HDAC2_HUMAN (625-1009): 4.6e-135: 417: 22.84
+	Hs
		1311358 ANKH1_HUMAN (2-123): 1.83e-29: 118: 13.82		HDAC2_HUMAN (625-1009): 4.6e-135: 417: 22.84
+	Hs
		292311 TRPA1_HUMAN (89-242): 3.61e-13: 70.9: 28.21		HDAC1_HUMAN (625-1009): 3.66e-145: 443: 23.35