HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 20206131
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 742
+	Mm
		139221 LEG9_MOUSE (1-355): 9.7e-137: 394: 69.30		CD44_MOUSE (1-742): 0: 540: 65.90
+	Hs
		121100 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		555071 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		449175 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		530369 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		CSPG2_HUMAN (13-660): 1.02e-75: 269: 14.86
+	Hs
		449171 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		CSPG2_HUMAN (13-660): 1.02e-75: 269: 14.86