HitPredict

Interactor 1: DTX2 (Q86UW9)
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2)
Gene: DTX2

Interactor 2: MED15 (Q96RN5)
Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)
Gene: MED15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35198878
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 622 Hs			1 788
+	Hs
		160072 DTX2_HUMAN (1-622): 0: 572: 100.00		HGS_HUMAN (71-479): 3.22e-23: 107: 18.08
+	Hs
		131731 DTX2_HUMAN (1-622): 0: 572: 100.00		BCL9_HUMAN (76-549): 7.24e-09: 61.7: 11.02
+	Hs
		160107 DTX3L_HUMAN (340-614): 3.96e-77: 261: 35.94		HGS_HUMAN (71-479): 3.22e-23: 107: 18.08
+	Hs
		302269 SC24C_HUMAN (165-522): 3.33e-33: 138: 13.71		SC31A_HUMAN (137-649): 5.31e-32: 136: 16.60
+	Hs
		297843 SC24D_HUMAN (265-547): 4.63e-09: 61.6: 13.33		SC31A_HUMAN (137-649): 5.31e-32: 136: 16.60
+	Mm
		1351630 PCLO_MOUSE (141-536): 3.66e-10: 65.4: 12.64		PCLO_MOUSE (71-586): 1.67e-10: 67.1: 9.49
+	Dm
		113976 M9PB30_DROME (276-523): 7.49e-11: 67.7: 12.00		M9PB30_DROME (74-691): 8.14e-09: 61.7: 8.44