Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4
Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.68 | 1.00 | 0.827 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_4~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2 |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0032733 - positive regulation of interleukin-10 production GO:0032735 - positive regulation of interleukin-12 production and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
