HitPredict

Interactor 1: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Interactor 2: SGK3 (Q96BR1)
Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)
Gene: SGK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 496
+	Hs
		1202133 HS904_HUMAN (1-418): 0: 548: 100.00		AKT3_HUMAN (20-493): 5.83e-165: 476: 38.27
+	Hs
		1202124 HS904_HUMAN (1-418): 0: 548: 100.00		SGK2_HUMAN (129-495): 4.78e-151: 437: 66.76
+	Hs
		461792 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		SGK3_HUMAN (1-496): 0: 546: 100.00
+	Hs
		462058 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		AKT3_HUMAN (20-493): 5.83e-165: 476: 38.27
+	Hs
		461164 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KPCL_HUMAN (28-493): 1.12e-161: 475: 33.33
+	Hs
		461190 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		AKT1_HUMAN (20-491): 8.46e-163: 471: 36.48
+	Hs
		461191 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		AKT2_HUMAN (20-490): 5e-162: 469: 36.63
+	Hs
		122902 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		SGK1_HUMAN (86-495): 6.22e-162: 467: 66.59
+	Hs
		461385 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KPCT_HUMAN (1-496): 2.29e-156: 462: 28.44
+	Hs
		461390 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KPCD_HUMAN (1-496): 9.55e-157: 462: 29.74
+	Hs
		461239 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KPCI_HUMAN (2-490): 1.88e-155: 457: 32.20
+	Hs
		461389 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KPCZ_HUMAN (2-490): 7.85e-153: 450: 30.73
+	Hs
		461373 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KPCE_HUMAN (55-487): 9.43e-150: 447: 35.85
+	Hs
		461158 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KS6B1_HUMAN (88-491): 7.9e-150: 440: 39.02
+	Hs
		461948 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		SGK2_HUMAN (129-495): 4.78e-151: 437: 66.76
+	Hs
		462003 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KS6B2_HUMAN (122-491): 2.07e-147: 432: 41.87
+	Hs
		461291 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KS6A3_HUMAN (5-432): 6.63e-109: 341: 23.87
+	Hs
		461505 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KS6A1_HUMAN (47-423): 3.25e-95: 305: 26.55
+	Hs
		461502 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KS6A2_HUMAN (58-474): 1.15e-93: 301: 25.06
+	Hs
		462023 HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42		KS6A6_HUMAN (162-419): 4.31e-87: 284: 27.88