Interactor 1: M9PF46 (M9PF46)
ribose-phosphate diphosphokinase (EC 2.7.6.1)
Gene: Prps

Interactor 2: Q8IMI0 (Q8IMI0)
LD38861p (LP08261p) (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform G (EC 2.7.6.1))
Gene: DmelCG2246

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 14605208, 37061542, 22036573
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0005737 - cytoplasm
GO:0006015 - 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006164 - purine nucleotide biosynthetic process
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 373
Dm

1 387
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025