Protein: KPR1
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 1)

Gene: KPR1, PRS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P32895

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

746727

KPR3
Ribose-phosphate pyrophosphokinase 3

8

18

Small-scale

0.967

High

746726

KPR2
Ribose-phosphate pyrophosphokinase 2

4

18

Small-scale

0.896

High

746723

KPR4
Ribose-phosphate pyrophosphokinase 4

3

18

Small-scale

0.849

High

746764

KPR5
Ribose-phosphate pyrophosphokinase 5

3

18

Small-scale

0.849

High

746717

KPR1
Ribose-phosphate pyrophosphokinase 1

1

18

High-throughput

0.698

High

746749

SLT2
Mitogen-activated protein kinase SLT2/MPK1

2

9

Small-scale

0.586

High

523457

HSP71
Heat shock protein SSA1

2

9

High-throughput

0.584

High

746751

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

746738

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

7

High-throughput

0.533

High

441080

KAPA
cAMP-dependent protein kinase type 1

1

3

High-throughput

0.501

High

602377

PHO85
Cyclin-dependent protein kinase PHO85

1

5

High-throughput

0.501

High

646119

NPR1
Nitrogen permease reactivator protein

1

2

High-throughput

0.501

High

673691

KCC4
Probable serine/threonine-protein kinase KCC4

1

7

High-throughput

0.501

High

738019

MKK1
MAP kinase kinase MKK1/SSP32

1

2

High-throughput

0.501

High

745268

ELM1
Serine/threonine-protein kinase ELM1

1

1

High-throughput

0.501

High

746718

SWE1
Mitosis inhibitor protein kinase SWE1

1

10

High-throughput

0.501

High

746724

CHK1
Serine/threonine-protein kinase CHK1

1

5

High-throughput

0.501

High

746740

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

High-throughput

0.501

High

746754

PKH3
Serine/threonine-protein kinase PKH3

1

2

High-throughput

0.501

High

746761

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

4

High-throughput

0.501

High

746763

PKH2
Serine/threonine-protein kinase PKH2

1

9

High-throughput

0.501

High

746742

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

3

High-throughput

0.489

High

746755

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.489

High

598387

TUP1
General transcriptional corepressor TUP1

1

1

Small-scale

0.481

High

746729

KOG1
Target of rapamycin complex 1 subunit KOG1

1

3

High-throughput

0.481

High

709334

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.480

High

746743

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.480

High

746756

TDA1
Serine/threonine-protein kinase TDA1

1

0

High-throughput

0.480

High

486111

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.479

High

558654

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

679520

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

726884

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

746733

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.479

High

746745

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.479

High

746746

CBK1
Serine/threonine-protein kinase CBK1

1

1

High-throughput

0.479

High

746766

DBP10
ATP-dependent RNA helicase DBP10

1

6

High-throughput

0.479

High

694120

CDC15
Cell division control protein 15

1

0

High-throughput

0.458

High

739937

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.458

High

746721

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

746728

TDA3
Putative oxidoreductase TDA3

1

0

High-throughput

0.458

High

746735

YAT2
Carnitine O-acetyltransferase YAT2

1

0

High-throughput

0.458

High

746739

FYV8
Protein FYV8

1

0

High-throughput

0.458

High

746741

BPL1
Biotin--protein ligase

1

0

High-throughput

0.458

High

746744

PNC1
Nicotinamidase

1

0

High-throughput

0.458

High

746747

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

746757

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

746759

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.457

High

741247

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

746736

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

746719

NUF2
Kinetochore protein NUF2

1

5

Small-scale

0.439

High

746762

RLM1
Transcription factor RLM1

1

2

Small-scale

0.439

High

670512

SIS1
Protein SIS1

1

5

High-throughput

0.437

High

706615

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

746732

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

746748

H3
Histone H3

1

2

High-throughput

0.437

High

746750

CTF4
DNA polymerase alpha-binding protein

1

4

High-throughput

0.437

High

746758

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

746734

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

746720

SPT7
SAGA complex subunit SPT7

1

3

High-throughput

0.407

High

746730

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.279

Low

746752

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.279

Low

746722

RPF2
Ribosome biogenesis protein RPF2

1

0

Small-scale

0.249

Low

746725

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.249

Low

746731

TEM1
Protein TEM1

1

0

High-throughput

0.249

Low

746737

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

746753

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.249

Low

746760

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

746765

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025