Interactor 1: FBRL (P15646)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U3 small nucleolar RNA-associated protein NOP1) (Nucleolar protein 1) (U3 snoRNA-associated protein NOP1)
Gene: NOP1

Interactor 2: NOP56 (Q12460)
Nucleolar protein 56 (Ribosome biosynthesis protein SIK1) (Suppressor of I kappa b protein 1)
Gene: NOP56

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 9372940, 24352239, 15670595, 16554755, 18268104, 31756331, 29054886, 33483369, 12215523, 37968396, 18268103
Identification Methods affinity chromatography technology, tandem affinity purification, two hybrid, x-ray crystallography, pull down, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Fibrillarin~Nop, Fibrillarin~NOP5NT
Common GO terms GO:0000452 - snoRNA guided rRNA 2'-O-methylation
GO:0000494 - box C/D sno(s)RNA 3'-end processing
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 327
Sc

1 504
+ Hs
+ Hs
+ Ce
+ Sc
+ Ca
+ Pf
+ Ss
+ Af

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024