HitPredict

Interactor 1: KPRB (O60256)
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41)
Gene: PRPSAP2

Interactor 2: PRPS3 (P21108)
Ribose-phosphate pyrophosphokinase 3 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 1-like 1) (PRPS1-like 1) (Phosphoribosyl pyrophosphate synthase III) (PRS-III)
Gene: PRPS1L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 28514442, 33961781, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0005737 - cytoplasm
GO:0006015 - 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006164 - purine nucleotide biosynthetic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 369
Hs

1 318
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Last updated: 11Aug2025