HitPredict

Interactor 1: Q9VA53 (Q9VA53)
GH23275p (RE14037p) (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform H (EC 2.7.6.1))
Gene: DmelCG2246

Interactor 2: Q9VT32 (Q9VT32)
Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase II)
Gene: Prps

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 14605208, 38944040
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0005737 - cytoplasm
GO:0006015 - 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006164 - purine nucleotide biosynthetic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 406
Dm

1 350
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Ce

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Last updated: 11Aug2025