Interactor 1: TCAM1 (Q8IUC6)
TIR domain-containing adapter molecule 1 (TICAM-1) (Proline-rich, vinculin and TIR domain-containing protein B) (Putative NF-kappa-B-activating protein 502H) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (MyD88-3) (TIR domain-containing adapter protein inducing IFN-beta)
Gene: TICAM1

Interactor 2: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 14739303
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0010008 - endosome membrane
GO:0032481 - positive regulation of type I interferon production
GO:0032728 - positive regulation of interferon-beta production
GO:0045087 - innate immune response
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 712
Hs

1 503
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024