HitPredict

Interactor 1: RRP41 (Q9SP08)
Exosome complex component RRP41 homolog (Ribosomal RNA-processing protein 41) (AtRRP41) (AtRrp41p)
Gene: RRP41

Interactor 2: Q9ZUI4 (Q9ZUI4)
Ribosomal RNA-processing protein 43
Gene: At1g60080

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	25144737, 18160042
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RNase_PH~RNase_PH, RNase_PH~RNase_PH_C, RNase_PH_C~RNase_PH_C
Common GO terms	GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0034475 - U4 snRNA 3'-end processing GO:0071028 - nuclear mRNA surveillance
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 241 At			1 302
+	Hs
		1284978 EXOS4_HUMAN (1-236): 1.32e-80: 243: 47.68		EXOS8_HUMAN (18-299): 1.34e-80: 247: 35.34
+	At
		1337646 RRP41_ARATH (1-241): 2.08e-88: 262: 100.00		CER7L_ARATH (21-298): 9.12e-73: 228: 25.36
+	At
		1340946 RRP41_ARATH (1-241): 2.08e-88: 262: 100.00		CER7_ARATH (21-298): 5.65e-69: 222: 26.07
+	Hs
		1063768 EXOS4_HUMAN (1-236): 1.32e-80: 243: 47.68		EXOS7_HUMAN (23-299): 2.01e-75: 234: 23.83
+	At
		1324946 RRP41_ARATH (1-241): 2.08e-88: 262: 100.00		Q9FPI0_ARATH (21-298): 1.22e-67: 214: 24.74
+	Ss
		1358190 RRP41_SACS2 (2-234): 5.75e-81: 244: 43.35		RRP42_SACS2 (10-298): 5.02e-72: 225: 27.34
+	Hs
		986725 EXOS4_HUMAN (1-236): 1.32e-80: 243: 47.68		EXOS9_HUMAN (24-302): 2e-61: 202: 23.05
+	Mt
		191405 RRP41_METTH (9-234): 2.1e-77: 235: 45.58		RRP42_METTH (25-298): 1.67e-64: 205: 27.74
+	Sp
		194779 RRP41_SCHPO (1-235): 7.33e-70: 215: 39.83		RRP45_SCHPO (14-298): 2.03e-70: 221: 24.48
+	Dm
		1100455 Q9VK19_DROME (1-232): 1.82e-74: 227: 40.60		Q29QQ9_DROME (23-299): 2.05e-64: 206: 22.50
+	Dm
		1100452 Q8SYC8_DROME (1-232): 6.74e-74: 226: 40.17		Q29QQ9_DROME (23-299): 2.05e-64: 206: 22.50
+	At
		1352635 RRP41_ARATH (1-241): 2.08e-88: 262: 100.00		RRP41_ARATH (34-298): 8.97e-51: 169: 18.15
+	Sp
		194784 RRP41_SCHPO (1-235): 7.33e-70: 215: 39.83		RRP43_SCHPO (17-288): 6.91e-67: 211: 31.25
+	Sc
		809587 RRP41_YEAST (1-241): 6.82e-63: 198: 35.66		RRP45_YEAST (14-298): 2.73e-65: 208: 23.43
+	Hs
		1342611 EXOS4_HUMAN (1-236): 1.32e-80: 243: 47.68		EXOS4_HUMAN (28-278): 5.83e-48: 162: 17.65
+	At
		58618 RRP41_ARATH (1-241): 2.08e-88: 262: 100.00		RP41L_ARATH (37-298): 1.45e-39: 140: 15.85
+	Sp
		194775 RRP41_SCHPO (1-235): 7.33e-70: 215: 39.83		RRP41_SCHPO (26-298): 4.81e-44: 152: 16.67
+	Sc
		809605 RRP41_YEAST (1-241): 6.82e-63: 198: 35.66		RRP42_YEAST (21-299): 2.71e-40: 143: 15.23
+	At
		1340208 RRP41_ARATH (1-241): 2.08e-88: 262: 100.00		EXOS5_ARATH (37-249): 2.83e-16: 78.3: 18.61