HitPredict

Interactor 1: GCC2 (Q8IWJ2)
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Gene: GCC2

Interactor 2: SYNCI (Q9H7C4)
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)
Gene: SYNC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1684 Hs			1 482
+	Hs
		1313530 CP250_HUMAN (858-1684): 1.24e-23: 111: 11.32		SYNCI_HUMAN (1-482): 9.08e-167: 481: 100.00
+	Hs
		443532 PLEC_HUMAN (255-1682): 1.43e-31: 138: 10.06		VIME_HUMAN (154-456): 2.16e-104: 321: 21.70
+	Hs
		1068542 PLEC_HUMAN (255-1682): 1.43e-31: 138: 10.06		AINX_HUMAN (170-456): 1.08e-91: 289: 25.25
+	Hs
		318809 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		K2C75_HUMAN (133-477): 2.66e-77: 253: 16.80
+	Hs
		580132 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		K2C4_HUMAN (141-481): 3.59e-77: 252: 15.04
+	Hs
		781898 PLEC_HUMAN (255-1682): 1.43e-31: 138: 10.06		PERI_HUMAN (154-456): 6.88e-79: 255: 22.50
+	Mm
		677677 PLEC_MOUSE (1-822): 1.99e-18: 95: 9.36		DESM_MOUSE (154-456): 2.87e-88: 279: 20.76
+	Hs
		1061108 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		K2C72_HUMAN (142-466): 1.04e-65: 221: 16.04
+	Hs
		821662 PLEC_HUMAN (255-1682): 1.43e-31: 138: 10.06		K2C6C_HUMAN (133-481): 3.14e-63: 216: 16.89