HitPredict

Interactor 1: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: SNTA1 (Q61234)
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin-1)
Gene: SNTA1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	1.00	0.716

Property	Details
Experiments	11551227
Identification Methods	enzyme linked immunosorbent assay, surface plasmon resonance, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Mm			1 503
+	Oc
		107623 G1SR27_RABIT (1-217): 4.48e-72: 219: 99.54		SNTA1_RABIT (1-503): 1.14e-157: 459: 92.34
+	Hs
		987611 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		SNTA1_HUMAN (1-503): 1.56e-157: 459: 91.75
+	Hs
		440059 LCK_HUMAN (3-202): 4.02e-36: 134: 27.49		SNTB2_HUMAN (3-502): 1.35e-133: 399: 43.64
+	Hs
		841007 FRK_HUMAN (3-202): 6.21e-35: 131: 28.37		SNTB2_HUMAN (3-502): 1.35e-133: 399: 43.64
+	Hs
		440107 LCK_HUMAN (3-202): 4.02e-36: 134: 27.49		MPP7_HUMAN (33-492): 1.02e-64: 221: 13.49
+	Mm
		1221224 GRB2_MOUSE (1-217): 1.59e-72: 220: 100.00		DLG4_MOUSE (34-353): 2.36e-23: 105: 16.16
+	Hs
		987532 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		DLG4_HUMAN (34-353): 1.23e-23: 106: 17.17
+	Hs
		987771 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		LNX2_HUMAN (30-182): 8.26e-17: 85.3: 22.58
+	Hs
		987788 GRB2_HUMAN (1-217): 4.48e-72: 219: 99.54		LNX1_HUMAN (14-305): 4e-16: 83.4: 16.61
+	Hs
		168616 HCK_HUMAN (116-215): 5.18e-11: 63.1: 19.61		CSKP_HUMAN (39-456): 9.09e-64: 224: 12.95
+	Hs
		168615 LYN_HUMAN (135-215): 9.03e-11: 62.7: 24.10		CSKP_HUMAN (39-456): 9.09e-64: 224: 12.95
+	Hs
		440052 LCK_HUMAN (3-202): 4.02e-36: 134: 27.49		DLG1_HUMAN (54-359): 1.57e-21: 100: 18.79
+	Hs
		473476 HCK_HUMAN (116-215): 5.18e-11: 63.1: 19.61		GOPC_HUMAN (57-163): 1.05e-35: 140: 42.48
+	Hs
		584588 VAV_HUMAN (3-60): 1.48e-15: 76.5: 43.10		LIN7C_HUMAN (77-172): 4.21e-31: 121: 37.50
+	Hs
		463243 YES_HUMAN (161-215): 4.3e-12: 66.5: 28.07		LIN7C_HUMAN (77-172): 4.21e-31: 121: 37.50
+	Hs
		440486 FYN_HUMAN (161-215): 1.22e-13: 71.1: 31.58		DLG4_HUMAN (34-353): 1.23e-23: 106: 17.17
+	Rn
		723904 SRC_RAT (104-215): 7.18e-13: 68.8: 19.30		DLG4_RAT (34-353): 1.1e-23: 106: 17.17
+	Mm
		431355 SRC_MOUSE (75-215): 6.13e-12: 66.1: 17.48		DLG4_MOUSE (34-353): 2.36e-23: 105: 16.16
+	Hs
		162768 YES_HUMAN (161-215): 4.3e-12: 66.5: 28.07		NHRF1_HUMAN (79-247): 9.89e-24: 104: 17.78
+	Hs
		557396 SRC_HUMAN (160-215): 2.32e-11: 64.2: 31.03		LNX1_HUMAN (14-305): 4e-16: 83.4: 16.61