HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 197
+	Hs
		440390 FYN_HUMAN (1-543): 0: 584: 72.16		PTN4_HUMAN (43-187): 5.78e-33: 126: 29.14
+	Rn
		723904 SRC_RAT (1-543): 0: 601: 73.67		DLG4_RAT (14-196): 4.35e-23: 97.9: 22.87
+	Mm
		431355 SRC_MOUSE (1-543): 0: 599: 73.67		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		557396 SRC_HUMAN (1-543): 0: 602: 74.22		LNX1_HUMAN (14-179): 4e-17: 80.6: 22.02
+	Hs
		440486 FYN_HUMAN (1-543): 0: 584: 72.16		DLG4_HUMAN (14-196): 4.48e-23: 97.9: 22.87
+	Hs
		168616 HCK_HUMAN (1-541): 0: 545: 57.49		CSKP_HUMAN (13-194): 7.06e-31: 120: 20.53
+	Hs
		440059 LCK_HUMAN (83-541): 0: 542: 60.78		SNTB2_HUMAN (61-179): 3.01e-32: 123: 35.25
+	Hs
		440107 LCK_HUMAN (83-541): 0: 542: 60.78		MPP7_HUMAN (31-188): 8.35e-32: 122: 25.95
+	Mm
		440284 LCK_MOUSE (83-541): 0: 544: 60.78		DLG1_MOUSE (50-178): 1.03e-22: 96.7: 30.60
+	Hs
		440052 LCK_HUMAN (83-541): 0: 542: 60.78		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		463569 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		MPP7_HUMAN (31-188): 8.35e-32: 122: 25.95
+	Hs
		168615 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		CSKP_HUMAN (13-194): 7.06e-31: 120: 20.53
+	Hs
		841007 FRK_HUMAN (71-535): 2.12e-172: 498: 48.25		SNTB2_HUMAN (61-179): 3.01e-32: 123: 35.25
+	Hs
		362172 ABL1_HUMAN (41-543): 1.77e-161: 490: 39.10		PTN4_HUMAN (43-187): 5.78e-33: 126: 29.14
+	Hs
		440050 LCK_HUMAN (83-541): 0: 542: 60.78		PTN13_HUMAN (14-196): 3.05e-14: 72.5: 19.02
+	Hs
		473476 HCK_HUMAN (1-541): 0: 545: 57.49		GOPC_HUMAN (92-173): 2.59e-13: 69.3: 46.34
+	Hs
		463488 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		463486 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		PTN13_HUMAN (14-196): 3.05e-14: 72.5: 19.02
+	Hs
		840977 ABL2_HUMAN (9-543): 6.98e-166: 503: 37.96		SNX27_HUMAN (91-175): 2.6e-12: 66.6: 38.14
+	Hs
		710622 EPHA3_HUMAN (3-535): 2.06e-156: 473: 25.66		PTN13_HUMAN (14-196): 3.05e-14: 72.5: 19.02