HitPredict

Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1101 Hs			1 127
+	Hs
		1221679 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B1M_HUMAN (1-127): 6.74e-55: 169: 84.25
+	Hs
		1129824 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B2F_HUMAN (5-127): 1.83e-54: 168: 85.37
+	Hs
		1221621 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		1221678 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B1N_HUMAN (1-127): 1.22e-53: 166: 85.83
+	Hs
		241580 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		886152 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		1221680 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		420896 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04
+	Hs
		1274480 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		241662 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		918774 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Sc
		355931 SMC3_YEAST (51-1055): 7.78e-71: 260: 13.66		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Hs
		311555 SMC2_HUMAN (51-1055): 9.8e-55: 210: 11.41		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		241464 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25
+	Hs
		725122 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		725133 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		725214 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		725231 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		H2B1L_HUMAN (1-127): 1.35e-52: 163: 85.83
+	Hs
		1274476 MYH2_HUMAN (112-552): 2.43e-12: 73.9: 8.44		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37