HitPredict

Interactor 1: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Interactor 2: PHF19 (Q9CXG9)
PHD finger protein 19 (Polycomb-like protein 3)
Gene: PHF19

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 23104054, 22438827
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0035098 - ESC/E(Z) complex
GO:0045814 - negative regulation of gene expression, epigenetic
GO:0048863 - stem cell differentiation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 746
Mm

1 578
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+ Dm
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+ Sp
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Service provided by Combinatics, Japan

Last updated: 11Aug2025