HitPredict

Interactor 1: EZH1 (P70351)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1

Interactor 2: MTF2 (Q02395)
Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (mPCl2) (Zinc-regulated factor 1) (ZiRF1)
Gene: MTF2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	25680957, 20064376
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 747 Mm			1 593
+	Hs
		1368814 EZH1_HUMAN (1-747): 0: 841: 97.86		MTF2_HUMAN (1-593): 0: 859: 97.64
+	Hs
		1213573 EZH1_HUMAN (1-747): 0: 841: 97.86		PHF19_HUMAN (17-591): 0: 727: 44.88
+	Mm
		1036631 EZH2_MOUSE (8-746): 0: 708: 63.29		MTF2_MOUSE (1-593): 0: 859: 100.00
+	Hs
		1155942 EZH2_HUMAN (8-746): 0: 704: 63.03		MTF2_HUMAN (1-593): 0: 859: 97.64
+	Hs
		210321 EZH1_HUMAN (1-747): 0: 841: 97.86		PHF1_HUMAN (42-589): 0: 642: 39.32
+	Mm
		1222447 EZH2_MOUSE (8-746): 0: 708: 63.29		PHF19_MOUSE (17-591): 0: 728: 45.02
+	Hs
		1155450 EZH2_HUMAN (8-746): 0: 704: 63.03		PHF19_HUMAN (17-591): 0: 727: 44.88
+	Mm
		1222455 EZH2_MOUSE (8-746): 0: 708: 63.29		PHF1_MOUSE (42-589): 0: 660: 39.64
+	Hs
		210284 EZH2_HUMAN (8-746): 0: 704: 63.03		PHF1_HUMAN (42-589): 0: 642: 39.32
+	Dm
		837314 EZ_DROME (8-747): 0: 692: 49.56		PCL_DROME (50-576): 2.14e-152: 466: 24.82
+	Mm
		1036640 EHMT2_MOUSE (443-733): 5.56e-68: 246: 24.16		MTF2_MOUSE (1-593): 0: 859: 100.00
+	Hs
		216570 SUV91_HUMAN (397-732): 1.58e-73: 246: 22.19		MTF2_HUMAN (1-593): 0: 859: 97.64
+	Hs
		1434607 SUV92_HUMAN (380-735): 1.13e-71: 241: 20.38		MTF2_HUMAN (1-593): 0: 859: 97.64
+	Hs
		216454 SUV91_HUMAN (397-732): 1.58e-73: 246: 22.19		PHF19_HUMAN (17-591): 0: 727: 44.88
+	Hs
		1213589 SUV92_HUMAN (380-735): 1.13e-71: 241: 20.38		PHF19_HUMAN (17-591): 0: 727: 44.88
+	Hs
		1155860 EZH2_HUMAN (8-746): 0: 704: 63.03		ASH2L_HUMAN (192-450): 3.4e-48: 179: 14.75
+	Dm
		633979 TRX_DROME (582-733): 1.79e-51: 196: 33.33		ASH2_DROME (190-476): 6.44e-73: 245: 17.97
+	Hs
		1041602 KMT2A_HUMAN (620-734): 4.38e-19: 95.1: 42.24		CSR2B_HUMAN (207-550): 3.52e-91: 299: 22.38
+	Sp
		237938 SET1_SCHPO (609-731): 9.8e-23: 106: 43.20		ASH2_SCHPO (183-449): 6.21e-77: 258: 18.73
+	Dm
		1306739 TRR_DROME (612-733): 3.84e-19: 95.1: 41.46		ASH2_DROME (190-476): 6.44e-73: 245: 17.97