HitPredict

Interactor 1: ACTN1 (Q7TPR4)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21653829
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005884 - actin filament
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 892 Mm			1 1161
+	Hs
		555731 ACTN1_HUMAN (1-892): 0: 671: 99.22		TSC1_HUMAN (1-1161): 0: 749: 86.98
+	Hs
		773768 ACTN2_HUMAN (10-892): 0: 610: 80.07		TSC1_HUMAN (1-1161): 0: 749: 86.98
+	Hs
		156898 ACTN1_HUMAN (1-892): 0: 671: 99.22		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		555621 ACTN1_HUMAN (1-892): 0: 671: 99.22		MYH9_HUMAN (773-1161): 6.5e-11: 69.1: 10.22
+	Hs
		156729 ACTN4_HUMAN (11-892): 0: 616: 86.51		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		157282 ACTN3_HUMAN (18-892): 0: 614: 78.06		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Dm
		432166 ACTN_DROME (2-892): 0: 625: 67.28		MYSA_DROME (432-1117): 1.1e-18: 94.5: 11.02
+	Hs
		157023 ACTN2_HUMAN (10-892): 0: 610: 80.07		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		224766 ACTN4_HUMAN (11-892): 0: 616: 86.51		MY18A_HUMAN (355-910): 4.2e-21: 102: 9.50
+	Mm
		945615 ACTN4_MOUSE (11-892): 0: 613: 86.51		MYH6_MOUSE (312-851): 1.93e-12: 74.2: 7.95
+	Hs
		224639 ACTN4_HUMAN (11-892): 0: 616: 86.51		MYH9_HUMAN (773-1161): 6.5e-11: 69.1: 10.22
+	Hs
		156700 SPTN2_HUMAN (243-805): 1.1e-15: 84.3: 13.12		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		174788 SPTN2_HUMAN (243-805): 1.1e-15: 84.3: 13.12		MY18A_HUMAN (355-910): 4.2e-21: 102: 9.50
+	Hs
		157250 SPTB2_HUMAN (165-808): 7.57e-11: 68.5: 12.07		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		156889 SPTB1_HUMAN (221-798): 9.3e-11: 68.2: 11.30		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		157840 SPTN4_HUMAN (228-707): 3.17e-10: 66.6: 11.89		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		1028834 SPTB2_HUMAN (165-808): 7.57e-11: 68.5: 12.07		MY18A_HUMAN (355-910): 4.2e-21: 102: 9.50
+	Hs
		174713 SPTN2_HUMAN (243-805): 1.1e-15: 84.3: 13.12		MYH9_HUMAN (773-1161): 6.5e-11: 69.1: 10.22
+	Dm
		1269943 Q7KV70_DROME (363-731): 3.13e-11: 69.7: 16.40		Q9VCC9_DROME (772-1075): 4.3e-11: 69.5: 8.60
+	Hs
		772748 SPTB2_HUMAN (165-808): 7.57e-11: 68.5: 12.07		MYH9_HUMAN (773-1161): 6.5e-11: 69.1: 10.22