HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30581152, 33545068
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 440
+	Hs
		1036954 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1031313 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		516499 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Dr
		94548 PABPA_DANRE (74-342): 2.56e-10: 65.4: 8.60		MIB1_DANRE (105-233): 1.14e-42: 162: 24.43
+	Hs
		319847 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		1056028 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		319819 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		319701 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50