HitPredict

Interactor 1: KBTB6 (Q86V97)
Kelch repeat and BTB domain-containing protein 6
Gene: KBTBD6

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated protein 1 light chain 3 beta (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (Microtubule-associated proteins 1A/1B light chain 3B) (MAP1A/MAP1B LC3 B) (MAP1A/MAP1B light chain 3 B)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	25684205, 20562859
Identification Methods	pull down, unspecified method, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, isothermal titration calorimetry, nuclear magnetic resonance
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	ATG8~KBTB_W-LIR
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 674 Hs			1 125
+	Hs
		1358849 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		1358856 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		952265 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328087 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1358844 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		1358852 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1290302 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		952228 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328058 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1290293 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		1290299 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Dm
		1269043 Q7KSF5_DROME (435-673): 2.29e-48: 183: 13.93		Q9W2S2_DROME (7-122): 5.2e-54: 166: 31.03
+	Hs
		1121519 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		1121526 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		952160 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328002 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1121523 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1399935 KLHL5_HUMAN (256-483): 9.34e-27: 118: 14.59		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		1199032 KLH12_HUMAN (505-673): 2.53e-25: 112: 13.37		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		952295 KLHL5_HUMAN (256-483): 9.34e-27: 118: 14.59		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47