HitPredict

Interactor 1: KBTB6 (Q86V97)
Kelch repeat and BTB domain-containing protein 6
Gene: KBTBD6

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.866

Property	Details
Experiments	25684205, 20562859
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down, unspecified method, anti tag coimmunoprecipitation, isothermal titration calorimetry, nuclear magnetic resonance
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	ATG8~KBTB_W-LIR
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 674 Hs			1 117
+	Hs
		952265 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1358852 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		328087 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		952228 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		328058 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		1358844 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		MLP3C_HUMAN (5-116): 1.62e-44: 143: 39.47
+	Hs
		1358856 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1358849 KBTB7_HUMAN (1-674): 1.55e-165: 492: 89.76		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1290293 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		MLP3C_HUMAN (5-116): 1.62e-44: 143: 39.47
+	Hs
		1290302 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1290297 KBTB6_HUMAN (1-674): 8.93e-160: 477: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Dm
		1269043 Q7KSF5_DROME (435-673): 2.29e-48: 183: 13.93		Q9W2S2_DROME (1-116): 1.57e-57: 175: 85.35
+	Hs
		952160 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1121523 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		328002 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		952295 KLHL5_HUMAN (256-483): 9.34e-27: 118: 14.59		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1121526 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1121519 KEAP1_HUMAN (471-673): 8.13e-37: 148: 13.99		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1399935 KLHL5_HUMAN (256-483): 9.34e-27: 118: 14.59		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1199032 KLH12_HUMAN (505-673): 2.53e-25: 112: 13.37		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62