HitPredict

Interactor 1: RNF41 (Q8BH75)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.528

Property	Details
Experiments	19483718
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Mm			1 729
+	Hs
		623583 RO52_HUMAN (3-295): 9.72e-59: 197: 16.94		TBK1_HUMAN (1-729): 0: 559: 94.10
+	Hs
		1089280 TRI26_HUMAN (3-301): 1.89e-49: 174: 12.62		TBK1_HUMAN (1-729): 0: 559: 94.10
+	Hs
		1458955 TRI10_HUMAN (3-279): 2.83e-47: 167: 16.84		TBK1_HUMAN (1-729): 0: 559: 94.10
+	Hs
		572267 TRI27_HUMAN (3-275): 3.41e-46: 165: 14.75		TBK1_HUMAN (1-729): 0: 559: 94.10
+	Mm
		1223831 TRI27_MOUSE (3-275): 6.74e-46: 164: 15.11		TBK1_MOUSE (1-729): 0: 554: 100.00
+	Hs
		1122552 TRIM6_HUMAN (11-296): 7.22e-51: 176: 18.24		IKKE_HUMAN (1-715): 1.69e-148: 451: 48.54
+	Hs
		571971 TRI27_HUMAN (3-275): 3.41e-46: 165: 14.75		IKKE_HUMAN (1-715): 1.69e-148: 451: 48.54
+	Hs
		167815 RO52_HUMAN (3-295): 9.72e-59: 197: 16.94		IKKB_HUMAN (9-709): 3.51e-131: 408: 18.37
+	Hs
		167808 TRI27_HUMAN (3-275): 3.41e-46: 165: 14.75		IKKB_HUMAN (9-709): 3.51e-131: 408: 18.37
+	Hs
		623109 RO52_HUMAN (3-295): 9.72e-59: 197: 16.94		CDK2_HUMAN (6-312): 1.86e-119: 361: 20.65
+	Hs
		1396678 RNF41_HUMAN (1-317): 1.79e-86: 264: 99.69		MARK4_HUMAN (9-311): 1.55e-86: 290: 25.16
+	Hs
		177906 TRI22_HUMAN (3-300): 1.95e-51: 178: 16.88		IKKA_HUMAN (9-643): 4.75e-119: 375: 20.06
+	Hs
		177781 TRI27_HUMAN (3-275): 3.41e-46: 165: 14.75		IKKA_HUMAN (9-643): 4.75e-119: 375: 20.06
+	Hs
		668060 TRI10_HUMAN (3-279): 2.83e-47: 167: 16.84		CDK2_HUMAN (6-312): 1.86e-119: 361: 20.65
+	Hs
		1390307 TRI11_HUMAN (3-295): 1.05e-55: 189: 13.92		MARK1_HUMAN (9-407): 4.28e-86: 290: 24.57
+	Hs
		279116 RO52_HUMAN (3-295): 9.72e-59: 197: 16.94		ULK1_HUMAN (13-222): 3.42e-26: 117: 34.10
+	Hs
		943585 TRI68_HUMAN (3-295): 8e-56: 190: 15.41		HUNK_HUMAN (15-224): 2.86e-21: 100: 33.95
+	Hs
		279111 TRI27_HUMAN (3-275): 3.41e-46: 165: 14.75		ULK1_HUMAN (13-222): 3.42e-26: 117: 34.10
+	Mm
		266960 TRI27_MOUSE (3-275): 6.74e-46: 164: 15.11		ULK1_MOUSE (13-222): 6.34e-26: 116: 33.64
+	Hs
		1420643 TRI39_HUMAN (9-271): 1.2e-47: 168: 16.54		DCLK3_HUMAN (14-238): 8.06e-23: 105: 30.22